SLC25A6 Antibody (Center) | MyBioSource MBS9213096 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SLC25A6 Antibody (Center)

catalog :

MBS9213096

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

SLC25A6 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SLC25A6 antibody detected the SLC25A6 protein (arrow).

image 2 :

SLC25A6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC25A6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

image 3 :

Confocal immunofluorescent analysis of SLC25A6 Antibody (Center) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

product information

catalog number :

MBS9213096

products type :

Antibody

products full name :

SLC25A6 Antibody (Center)

products short name :

[SLC25A6]

products name syn :

[ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein; isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6; ADP/ATP translocase 3; N-terminally processed; SLC25A6; ANT3]

other names :

[ADP/ATP translocase 3; ADP/ATP translocase 3; ADP/ATP translocase 3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; ADP,ATP carrier protein 3; ADP,ATP carrier protein, isoform T2; ANT 2]

products gene name :

[SLC25A6]

other gene names :

[SLC25A6; SLC25A6; 2; 3; ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y; ANT3; ANT 2; ANT 3]

uniprot entry name :

ADT3_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence positions :

[128-155]

sequence length :

298

specificity :

This SLC25A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human SLC25A6.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.44

storage stability :

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. IHC-P~~1:10~50. IF~~1:10~50. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Immunofluorescence (IF)

image4 heading :

Flow Cytometry (FC/FACS)

image4 description :

SLC25A6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Clone Names: RB32242. Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Cellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.

products categories :

Cell Biology; Metabolism; Signal Transduction

products description :

This gene is a member of the mitochondrial carrier. subfamily of solute carrier protein genes. The product of this gene. functions as a gated pore that translocates ADP from the. mitochondrial matrix into the cytoplasm. The protein is implicated. in the function of the permability transition pore complex (PTPC),. which regulates the release of mitochondrial products that induce. apoptosis. The human genome contains several non-transcribed. pseudogenes of this gene.

products references :

Danishuddin, M., et al. J Mol Model 16(3):535-541(2010). Hu, Z., et al. FEBS Lett. 583(2):383-388(2009). Yang, Z., et al. Mol. Biol. Cell 18(11):4681-4689(2007). Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007). Jang, J.Y., et al. Cell. Immunol. 241(1):14-25(2006)

ncbi gi num :

156071462

ncbi acc num :

NP_001627.2

ncbi gb acc num :

NM_001636.3

uniprot acc num :

P12236

ncbi mol weight :

32866

ncbi pathways :

Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293); Ascorbate And Aldarate Metabolism Pathway (293)

ncbi summary :

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Jun 2013]

uniprot summary :

SLC25A6: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Belongs to the mitochondrial carrier family. Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Mitochondrial; Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp22.32 and Yp11.3. Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane; nucleus; mitochondrial inner membrane presequence translocase complex. Molecular Function: protein binding; ATP:ADP antiporter activity. Biological Process: ATP transport; ADP transport; cellular protein metabolic process; viral reproduction; apoptosis; active induction of host immune response by virus; virus-host interaction; energy reserve metabolic process; viral infectious cycle; protein targeting to mitochondrion; regulation of insulin secretion; transmembrane transport

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage