catalog number :
MBS9212905
products full name :
PADI6 Antibody (N-term)
products short name :
[PADI6]
products name syn :
[Protein-arginine deiminase type-6; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI; PADI6]
other names :
[protein-arginine deiminase type-6; Protein-arginine deiminase type-6; protein-arginine deiminase type-6; peptidyl arginine deiminase, type VI; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI]
products gene name :
[PADI6]
other gene names :
[PADI6; PADI6; hPADVI; hPADVI]
uniprot entry name :
PADI6_HUMAN
reactivity :
Human, mouse
sequence positions :
[196-223]
specificity :
This PADI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-223 amino acids from the N-terminal region of human PADI6.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
other info1 :
Calculated MW: 77727
products description :
Peptidylarginine deiminases (PADs, EC 3.5.3.15), including. PADI6, make up a family of posttranslational protein modification. enzymes that convert arginine residues to citrulline residues in. the presence of calcium ions.
products references :
Stacey, S.N., et al. Nat. Genet. 40(11):1313-1318(2008). Chavanas, S., et al. Gene 330, 19-27 (2004) :. Zhang, J., et al. Acta Biochim. Pol. 51(4):1051-1058(2004). Vossenaar, E.R., et al. Bioessays 25(11):1106-1118(2003)
ncbi acc num :
NP_997304.3
ncbi gb acc num :
NM_207421.4
ncbi pathways :
, Pathway (353238); , Pathway (353238)
ncbi summary :
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]
uniprot summary :
PADI6: Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo. Belongs to the protein arginine deiminase family. Protein type: Cytoskeletal; Hydrolase; EC 3.5.3.15. Chromosomal Location of Human Ortholog: 1p36.13. Cellular Component: intermediate filament cytoskeleton; cytoplasm; nucleus. Molecular Function: calcium ion binding; protein-arginine deiminase activity. Biological Process: translational machinery localization; cytoskeleton organization and biogenesis; cytoplasm organization and biogenesis; peptidyl-citrulline biosynthetic process from peptidyl-arginine