RSF1 Antibody (C-term) | MyBioSource MBS9212870 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

RSF1 Antibody (C-term)

catalog :

MBS9212870

quantity :

0.08 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9212870

products type :

Antibody

products full name :

RSF1 Antibody (C-term)

products short name :

RSF1

products name syn :

Remodeling and spacing factor 1; Rsf-1; HBV pX-associated protein 8; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complex; RSF1; HBXAP; XAP8

other names :

remodeling and spacing factor 1; Remodeling and spacing factor 1; remodeling and spacing factor 1; remodeling and spacing factor 1; HBV pX-associated protein 8; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complex

products gene name :

RSF1

other gene names :

RSF1; RSF1; XAP8; p325; HBXAP; RSF-1; HBXAP; XAP8; Rsf-1

uniprot entry name :

RSF1_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence length :

1441

specificity :

This RSF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1355-1389 amino acids from the C-terminal region of human RSF1.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

other info1 :

Crown Antibody: Yes. Precautions: RSF1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. Cellular Location: Nucleus. Tissue Location: Ubiquitously expressed.

other info2 :

Antigen Source: HUMAN

products categories :

Crown Antibodies; Signal Transduction

products description :

Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain.

products references :

Shamay M.,et al.Genomics 79:523-529(2002). Shamay M.,et al.J. Biol. Chem. 277:9982-9988(2002). Taylor T.D.,et al.Nature 440:497-500(2006). Mao Y.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).

ncbi gi num :

38788333

ncbi acc num :

NP_057662.3

ncbi gb acc num :

NM_016578.3

uniprot acc num :

Q96T23

ncbi mol weight :

163821

ncbi pathways :

Butanoate Metabolism Pathway (51773); Butanoate Metabolism Pathway (51773); Butanoate Metabolism Pathway (51773); Butanoate Metabolism Pathway (51773)

ncbi summary :

This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011]

uniprot summary :

HBXAP: Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 11q14.1. Cellular Component: nucleoplasm; RSF complex; nucleus. Molecular Function: protein binding; zinc ion binding; histone binding; ATPase activity. Biological Process: chromatin remodeling; nucleosome assembly; DNA replication-independent nucleosome assembly at centromere; positive regulation of viral transcription; positive regulation of transcription, DNA-dependent; transcription initiation; negative regulation of transcription, DNA-dependent; negative regulation of DNA binding; nucleosome positioning

size1 :

0.08 mL

price1 :

155 USD

size2 :

0.4 mL

price2 :

340

more info or order :

MyBioSource product webpage