ARL6IP5 Antibody (Center) | MyBioSource MBS9212515 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ARL6IP5 Antibody (Center)

catalog :

MBS9212515

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

ARL6IP5 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the ARL6IP5 antibody detected the ARL6IP5 protein (arrow).

product information

catalog number :

MBS9212515

products type :

Antibody

products full name :

ARL6IP5 Antibody (Center)

products short name :

[ARL6IP5]

products name syn :

[PRA1 family protein 3; ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; GTRAP3-18; Glutamate transporter EAAC1-interacting protein; JM5; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK-activating protein PM27; ARL6IP5; DERP11; JWA; PRA2; PRAF3]

other names :

[PRA1 family protein 3; PRA1 family protein 3; PRA1 family protein 3; ADP-ribosylation factor-like 6 interacting protein 5; ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5; Cytoskeleton-related vitamin A-responsive protein; Dermal papilla-derived protein 11; GTRAP3-18; Glutamate transporter EAAC1-interacting protein; JM5; Prenylated Rab acceptor protein 2; Protein JWa; Putative MAPK-activating protein PM27]

products gene name :

[ARL6IP5]

other gene names :

[ARL6IP5; ARL6IP5; JWA; jmx; hp22; PRAF3; DERP11; HSPC127; addicsin; GTRAP3-18; DERP11; JWA; PRA2; PRAF3; ARL-6-interacting protein 5; Aip-5]

uniprot entry name :

PRAF3_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, mouse

sequence positions :

[70-99]

sequence length :

188

specificity :

This ARL6IP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the Central region of human ARL6IP5.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

image1 heading :

Western Blot (WB)

other info2 :

Calculated MW: 21615. Function: Regulates intracellular concentrations oftaurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. May be involved in membrane traffic. Cellular location: Endoplasmic reticulum membrane {ECO:0000250 UniProtKB:Q9ES40}; Multi-pass membrane protein. Cell membrane {ECO:0000250 UniProtKB:Q9ES40}; Multi-pass membrane protein. Cytoplasm {ECO:0000250 UniProtKB:Q9ES40}. Cytoplasm, cytoskeleton {ECO:0000250 UniProtKB:Q9ES40}.Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules {ECO:0000250 UniProtKB:Q9ES40

products categories :

Cell Biology; Signal Transduction

products description :

Expression of this gene is affected by vitamin A. The. encoded protein of this gene may be associated with the. cytoskeleton. A similar protein in rats may play a role in the. regulation of cell differentiation. The rat protein binds and. inhibits the cell membrane glutamate transporter EAAC1. The. expression of the rat gene is upregulated by retinoic acid, which. results in a specific reduction in EAAC1-mediated glutamate. transport.

products references :

Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010). Akiduki, S., et al. J. Biol. Chem. 283(46):31323-31332(2008). Ruggiero, A.M., et al. J. Biol. Chem. 283(10):6175-6183(2008). Watabe, M., et al. Mol. Pharmacol. 72(5):1103-1110(2007). Zhu, Y.J., et al. J. Toxicol. Environ. Health Part A 70(11):895-900(2007)

ncbi gi num :

5453704

ncbi acc num :

NP_006398.1

ncbi gb acc num :

NM_006407.3

uniprot acc num :

O75915

ncbi pathways :

Riboflavin Metabolism Pathway (10550); Riboflavin Metabolism Pathway (10550); Riboflavin Metabolism Pathway (10550); Riboflavin Metabolism Pathway (10550)

ncbi summary :

Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport. [provided by RefSeq, Jul 2008]

uniprot summary :

ARL6IP5: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. Belongs to the PRA1 family. Protein type: Cytoskeletal; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 3p14. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: protein C-terminus binding. Biological Process: L-glutamate transport; positive regulation of apoptosis; positive regulation of caspase activity; negative regulation of transport; induction of apoptosis by oxidative stress; positive regulation of stress-activated MAPK cascade

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage