DCL-1 Antibody (Center) | MyBioSource MBS9212379 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

DCL-1 Antibody (Center)

catalog :

MBS9212379

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of DCL-1 Antibody (Center) in mouse liver tissue lysates (35ug/lane). DCL-1 (arrow) was detected using the purified Pab.

image 2 :

Formalin-fixed and paraffin-embedded human hepatocarcinoma with DCL-1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

image 3 :

DCL-1 Antibody (Center) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9212379

products type :

Antibody

products full name :

DCL-1 Antibody (Center)

products short name :

[DCL-1]

products name syn :

[CD302 antigen; C-type lectin BIMLEC; C-type lectin domain family 13 member A; DEC205-associated C-type lectin 1; Type I transmembrane C-type lectin receptor DCL-1; CD302; CD302; CLEC13A; DCL1; KIAA0022]

other names :

[CD302 antigen isoform 2; CD302 antigen; CD302 antigen; CD302 molecule; C-type lectin BIMLEC; C-type lectin domain family 13 member A; DEC205-associated C-type lectin 1; Type I transmembrane C-type lectin receptor DCL-1; CD_antigen: CD302]

products gene name :

[CD302]

other gene names :

[CD302; CD302; DCL1; DCL-1; BIMLEC; CLEC13A; CLEC13A; DCL1; KIAA0022]

uniprot entry name :

CD302_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, mouse

sequence positions :

[143-170]

sequence length :

1,873

specificity :

This DCL-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-170 amino acids from the Central region of human DCL-1.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.466

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. IHC-P~~1:50~100. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Flow Cytometry (FC/FACS)

other info1 :

Antigen Type: Synthetic Peptide. Clone Names: RB19594

other info2 :

Antigen Source: Human. Function: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. Cellular Location: Membrane; Single-pass type I membrane protein. Cell projection, filopodium. Cytoplasm, cell cortex. Cell projection, microvillus. Note=Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface. Tissue Location: Expressed at moderate levels in monocytes, myeloid blood dendritic cells and granulocytes and at low levels in plasmacytoid blood dendritic cells, monocyte-derived ma crophages and monocyte-derived dendritic cells, with no expression detected in T-lymphocytes, B-lymphocytes and natural killer cells (at protein level). Expressed widely in different tissues, with highest expression levels in liver, lung, peripheral blood leukocytes and spleen, and lowest levels in neuronal tissues, skeletal muscle and ovary. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed- Sternberg (HRS) cells.

products description :

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis.

products references :

Kato,M., J. Immunol. 179 (9), 6052-6063 (2007)

ncbi gi num :

311771590

ncbi acc num :

NP_001185692.1

ncbi gb acc num :

NM_001198763.1

uniprot acc num :

Q8IX05

ncbi mol weight :

26183

ncbi summary :

CD302 is a C-type lectin receptor involved in cell adhesion and migration, as well as endocytosis and phagocytosis (Kato et al., 2007 [PubMed 17947679]).[supplied by OMIM, Aug 2008]

uniprot summary :

CD302: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 2q24.2. Cellular Component: microvillus; membrane; integral to membrane; cell cortex; filopodium. Molecular Function: carbohydrate binding. Biological Process: phagocytosis

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage