product summary
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company name :
MyBioSource
product type :
antibody
product name :
BRP44L Antibody (C-term)
catalog :
MBS9211639
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western blot analysis of lysates from Hela, K562 cell line, human liver tissue(from left to right), using BRP44L Antibody (C-term). MBS9211639 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
product information
catalog number :
MBS9211639
products type :
Antibody
products full name :
BRP44L Antibody (C-term)
products short name :
[BRP44L]
products name syn :
[Mitochondrial pyruvate carrier 1; Brain protein 44-like protein; MPC1; BRP44L]
other names :
[mitochondrial pyruvate carrier 1 isoform 1; Mitochondrial pyruvate carrier 1; mitochondrial pyruvate carrier 1; mitochondrial pyruvate carrier 1; Brain protein 44-like protein]
products gene name :
[MPC1]
other gene names :
[MPC1; MPC1; MPYCD; BRP44L; CGI-129; dJ68L15.3; BRP44L]
uniprot entry name :
MPC1_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human
sequence length :
109
specificity :
This BRP44L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 96-129 amino acids from the C-terminal region of human BRP44L.
purity :
Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
concentration :
Vial Concentration: 0.473
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB~~1:1000
image1 heading :
Western Blot (WB)
other info1 :
Crown Antibody: Yes
other info2 :
Antigen Source: HUMAN. Cellular Location: Mitochondrion inner membrane; Multi-pass membrane protein
products categories :
Crown Antibodies; Cell Biology
products description :
Mediates the uptake of pyruvate into mitochondria.
products references :
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000). Lai C.-H.,et al.Genome Res. 10:703-713(2000). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Yu W.-Q.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
ncbi gi num :
7706369
ncbi acc num :
NP_057182.1
ncbi gb acc num :
NM_016098.3
uniprot acc num :
Q9Y5U8
ncbi mol weight :
12347
ncbi summary :
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012]
uniprot summary :
BRP44L: Mediates the uptake of pyruvate into mitochondria. Defects in MPC1 are the cause of mitochondrial pyruvate carrier deficiency (MPYCD). An autosomal recessive metabolic disorder characterized by severely delayed psychomotor development, mild dysmorphic features, hepatomegaly, marked metabolic acidosis, hyperlactacidemia with normal lactate/pyruvate, and encephalopathy. Some patients have epilepsy and peripheral neuropathy. Belongs to the mitochondrial pyruvate carrier (MPC) family. Protein type: Membrane protein, multi-pass; Mitochondrial. Chromosomal Location of Human Ortholog: 6q27. Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane. Molecular Function: pyruvate transmembrane transporter activity. Biological Process: cellular metabolic process; mitochondrial pyruvate transport; pyruvate metabolic process. Disease: Mitochondrial Pyruvate Carrier Deficiency
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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