catalog number :
MBS9211506
products full name :
VWA2 Antibody (N-term)
products short name :
[VWA2]
products name syn :
[von Willebrand factor A domain-containing protein 2; A domain-containing protein similar to matrilin and collagen; AMACO; Colon cancer secreted protein 2; CCSP-2; VWA2; AMACO]
other names :
[von Willebrand factor A domain-containing protein 2; von Willebrand factor A domain-containing protein 2; von Willebrand factor A domain-containing protein 2; von Willebrand factor A domain containing 2; A domain-containing protein similar to matrilin and collagen; AMACO; Colon cancer secreted protein 2; CCSP-2]
products gene name :
[VWA2]
other gene names :
[VWA2; VWA2; AMACO; NET42; CCSP-2; AMACO; AMACO; CCSP-2]
uniprot entry name :
VWA2_HUMAN
sequence positions :
[44-72]
specificity :
This VWA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human VWA2.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
concentration :
Vial Concentration: 0.5
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
other info1 :
Antigen Type: Synthetic Peptide. Clone Names: RB31644
other info2 :
Antigen Source: HUMAN
products categories :
Cancer
products description :
VWA2, also named as AMACO and CCSP2, is a novel candidate serological marker of colon neoplasia. VWA2 is found in the media of variesy of established cell lines of both fibroblast and epithelial origin.
products references :
Gao, W., et al. Blood 112(5):1713-1719(2008). Gebauer, J.M., et al. J. Biol. Chem. 283(26):17846-17854(2008). Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006). Xin, B., et al. Oncogene 24(4):724-731(2005). Eller, E., et al. Ann. N. Y. Acad. Sci. 1037, 145-149 (2004) :
ncbi acc num :
NP_001258975.1
ncbi gb acc num :
NM_001272046.1
ncbi summary :
This gene encodes a member of the von Willebrand factor A-like domain protein superfamily. The encoded protein is localized to the extracellular matrix and may serve as a structural component in basement membranes or in anchoring structures on scaffolds of collagen VII or fibrillin. This gene has been linked to type 1A diabetes and is a candidate serological marker for colon cancer. [provided by RefSeq, Jan 2013]
uniprot summary :
VWA2: 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 10q25.3. Cellular Component: extracellular space; basement membrane. Molecular Function: identical protein binding. Biological Process: regulation of insulin receptor signaling pathway; calcium-independent cell-matrix adhesion; protein homooligomerization