catalog number :
MBS9211413
products full name :
MS4A7 Antibody (Center)
products short name :
[MS4A7]
products name syn :
[Membrane-spanning 4-domains subfamily A member 7; CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2; MS4A7; 4SPAN2; CD20L4; CFFM4]
other names :
[membrane-spanning 4-domains subfamily A member 7 isoform 1; Membrane-spanning 4-domains subfamily A member 7; membrane-spanning 4-domains subfamily A member 7; membrane-spanning 4-domains, subfamily A, member 7; CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2]
products gene name :
[MS4A7]
other gene names :
[MS4A7; MS4A7; CFFM4; MS4A8; 4SPAN2; CD20L4; 4SPAN2; CD20L4; CFFM4]
uniprot entry name :
MS4A7_HUMAN
sequence positions :
[137-164]
specificity :
This MS4A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human MS4A7.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
other info2 :
Tissue location: Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes. Cellular location: Membrane; Multi-pass membrane protein. Function: May be involved in signal transduction as a component of a multimeric receptor complex.
products categories :
Cell Biology
products description :
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by. RefSeq].
products references :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :. Gingras, M.C., et al. Immunogenetics 53(6):468-476(2001). Liang, Y., et al. Immunogenetics 53(5):357-368(2001). Liang, Y., et al. Genomics 72(2):119-127(2001). Ishibashi, K., et al. Gene 264(1):87-93(2001)
ncbi acc num :
NP_067024.1
ncbi gb acc num :
NM_021201.4
ncbi summary :
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
uniprot summary :
MS4A7: May be involved in signal transduction as a component of a multimeric receptor complex. Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11q12. Cellular Component: integral to membrane