catalog number :
MBS9210435
products full name :
HOXB5 Antibody (C-term)
products short name :
[HOXB5]
products name syn :
[Homeobox protein Hox-B5; Homeobox protein HHOC10; Homeobox protein Hox-2A; Homeobox protein Hu-1; HOXB5; HOX2A]
other names :
[homeobox protein Hox-B5; Homeobox protein Hox-B5; homeobox protein Hox-B5; homeobox B5; Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hu-1]
products gene name :
[HOXB5]
other gene names :
[HOXB5; HOXB5; HOX2; HU-1; HOX2A; Hox2.1; HHO.C10; HOX2A]
uniprot entry name :
HXB5_HUMAN
reactivity :
Human (Predicted Reactivity: Drosophila, Zebrafish, Chicken, Mouse, Sheep, Bovine, Rat, Xenopus)
sequence positions :
[193-222]
specificity :
This HOXB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from the C-terminal region of human HOXB5.
purity :
Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
app notes :
WB: 1:1000. FC: 1:10-50
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Flow Cytometry (FC/FACS)
other info1 :
Antigen Type: Synthetic Peptide
other info2 :
Antigen Source: Human. Tissue Location: Spinal Cord
products description :
HOXB5 is a nuclear protein with a homeobox DNA-binding domain. This protein functions as a sequence-specific transcription factor that is involved in lung and gut development.
products references :
Kosaki,K., et.al., Teratology 65 (2), 50-62 (2002)
ncbi acc num :
NP_002138.1
ncbi gb acc num :
NM_002147.3
ncbi summary :
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]
uniprot summary :
HOXB5: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 17q21.3. Cellular Component: nucleus. Biological Process: anterior/posterior pattern formation; endothelial cell differentiation; anatomical structure morphogenesis; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; embryonic skeletal morphogenesis