ADCY9 Antibody (C-term) | MyBioSource MBS9210037 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ADCY9 Antibody (C-term)

catalog :

MBS9210037

quantity :

0.08 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9210037

products type :

Antibody

products full name :

ADCY9 Antibody (C-term)

products short name :

ADCY9

products name syn :

Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9; ADCY9; KIAA0520

other names :

adenylate cyclase type 9; Adenylate cyclase type 9; adenylate cyclase type 9; adenylate cyclase 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9

products gene name :

ADCY9

other gene names :

ADCY9; ADCY9; AC9; KIAA0520

uniprot entry name :

ADCY9_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, mouse

sequence positions :

1295-1323

sequence length :

1353

specificity :

This ADCY9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1295-1323 amino acids from the C-terminal region of human ADCY9.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000. Cellular Location: Membrance; Multi-pass membrane protein. Tissue Location: Expressed in multiple cells of the lung, with expression highest in airway smooth muscle distributed adenlyl cyclase, and it is stimulate by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN

products categories :

Cancer; Metabolism; Signal Transduction

products description :

Adenylate cyclase is a membrane bound enzyme that. catalyses the formation of cyclic AMP from ATP. It is regulated by. a family of G protein-coupled receptors, protein kinases, and. calcium. The type 9 adenylyl cyclase is a widely distributed. adenylyl cyclase, and it is stimulated by beta-adrenergic receptor. activation but is insensitive to forskolin, calcium, and. somatostatin. Function: May play a fundamental role in situations where fine interphlay between intracellular calcium and cAMP determines the cellular function. May be a phyciologically relevant docking site for calcineurin (By similarity).

products references :

Wojcik, C., et al. Am. J. Med. Genet. A 152A (2), 479-483 (2010) :. Olsen, J.V., et al. Cell 127(3):635-648(2006). Tantisira, K.G., et al. Hum. Mol. Genet. 14(12):1671-1677(2005). Cumbay, M.G., et al. J. Pharmacol. Exp. Ther. 310(1):108-115(2004). Small, K.M., et al. Pharmacogenetics 13(9):535-541(2003)

ncbi gi num :

50959205

ncbi acc num :

NP_001107.2

ncbi gb acc num :

NM_001116.3

uniprot acc num :

O60503

ncbi mol weight :

150701

ncbi pathways :

Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115); Adenosine Nucleotides Degradation II Pathway (115)

ncbi summary :

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]

uniprot summary :

ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Protein type: Transporter, aquaporin family; Adenylyl cyclase; Nucleotide Metabolism - purine; Lyase; Transporter; EC 4.6.1.1; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity. Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; G-protein signaling, adenylate cyclase activating pathway; transmembrane transport

size1 :

0.08 mL

price1 :

155 USD

size2 :

0.4 mL

price2 :

340

more info or order :

MyBioSource product webpage