antibody

Mouse Cdk13 Antibody (N-term)

MBS9208374

0.08 mL

150 USD

polyclonal

rabbit

nonconjugated

western blot, ELISA, enzyme immunoassay

Antibody

Mouse Cdk13 Antibody (N-term)

[Cdk13]

[Cyclin-dependent kinase 13; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; Cdk13; Cdc2l5; Kiaa1791]

[cyclin-dependent kinase 13 isoform 1; Cyclin-dependent kinase 13; cyclin-dependent kinase 13; cyclin-dependent kinase 13; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13]

[Cdk13]

[Cdk13; Cdk13; Cdc2l5; 2310015O17Rik; Cdc2l5; Kiaa1791]

CDK13_MOUSE

Polyclonal

Rabbit Ig

Rabbit

Mouse

[282-310]

1,451

This Mouse Cdk13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the N-terminal region of mouse Cdk13.

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB), ELISA (EIA)

WB~~1:1000

Western Blot (WB)

Function: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. Cellular location: Nucleus speckle

Cdk13 may be a controller of the mitotic cell cycle. Involved in the blood cell development (By similarity).

124486698

NP_001074527.1

NM_001081058.2

Q69ZA1

CDK13: a CMGC protein kinase of the CDK family. It has been reported to interact with L-type cyclins. Overexpression of CDC2L5 constructs disturbs constitutive splicing and switches alternative splice site selection in vivo suggesting that it may regulate alternative splicing. It has unusually large N- and C-termini and is ubiquitously expressed in many tissues. Two alternatively spliced human isoforms have been described. Protein type: Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; RNA splicing; EC 2.7.11.23; Kinase, protein; EC 2.7.11.22; Cell cycle regulation; CMGC group; CDK family; CRK7 subfamily; CDK/CRK7 subfamily. Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; nuclear cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nuclear speck; nucleus. Molecular Function: transferase activity; RNA polymerase subunit kinase activity; protein serine/threonine kinase activity; cyclin binding; cyclin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity. Biological Process: alternative nuclear mRNA splicing, via spliceosome; RNA splicing; hemopoiesis; mRNA processing; phosphorylation; protein amino acid phosphorylation

0.08 mL

150 USD

0.4 mL

340