GIPC1 Antibody (N-term) | MyBioSource MBS9208255 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

GIPC1 Antibody (N-term)

catalog :

MBS9208255

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

All lanes : Anti-GIPC1 Antibody (N-term) at 1:2000 dilution . Lane 1: 293 whole cell lysate . Lane 2: Hela whole cell lysate . Lane 3: HepG2 whole cell lysate . Lane 4: U-251 MG whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), . Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36 kDa . Blocking/Dilution buffer: 5% NFDM/TBST.

image 2 :

All lanes : Anti-GIPC1 Antibody (N-term) at 1:2000 dilution . Lane 1: 293 whole cell lysate . Lane 2: Hela whole cell lysate . Lane 3: HepG2 whole cell lysate . Lane 4: U-251 MG whole cell lysate . Lane 5: Mouse brain lysate Lane . 6: Ratbrain lysate Lysates/proteins at 20 ug per lane.

product information

catalog number :

MBS9208255

products type :

Antibody

products full name :

GIPC1 Antibody (N-term)

products short name :

[GIPC1]

products name syn :

[C19orf3, GIPC, RGS19IP1]

other names :

[PDZ domain-containing protein GIPC1 isoform 1; PDZ domain-containing protein GIPC1; PDZ domain-containing protein GIPC1; GIPC PDZ domain containing family, member 1; GAIP C-terminus-interacting protein; RGS-GAIP-interacting protein; RGS19-interacting protein 1; Synectin; Tax interaction protein 2; TIP-2]

products gene name :

[GIPC1]

other gene names :

[GIPC1; GIPC1; NIP; GIPC; IIP-1; TIP-2; SEMCAP; C19orf3; Hs.6454; GLUT1CBP; RGS19IP1; SYNECTIN; SYNECTIIN; C19orf3; GIPC; RGS19IP1; TIP-2]

uniprot entry name :

GIPC1_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, mouse (Predicted Reactivity: Rat)

sequence positions :

[52-81]

sequence length :

specificity :

This GIPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human GIPC1.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

image1 heading :

Western Blot

image2 heading :

Western Blot (WB)

other info1 :

Function: May be involved in G protein-linked signaling. Cellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Location: Widely expressed

other info2 :

Clone Names: RB35840. Function: May be involved in G protein-linked signaling. Cellular Location: Cytoplasm. Membrane; Peripheral membraneprotein. Tissue Location: Widely expressed.

products categories :

Signal Transduction

products description :

GIPC1 is a scaffolding protein that regulates cell surface. receptor expression and trafficking (Lee et al., 2008 [PubMed. 18775991]).

products references :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Wu, D., et al. J. Biol. Chem. 285(37):28643-28650(2010). Razanskas, R., et al. Arch. Virol. 155(2):247-250(2010). Puri, C., et al. Oncogene 29(2):188-200(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

ncbi gi num :

5031715

ncbi acc num :

NP_005707.1

ncbi gb acc num :

NM_005716.3

uniprot acc num :

O14908

ncbi mol weight :

36049

ncbi pathways :

Ribosome Pathway (10755); Ribosome Pathway (10755); Ribosome Pathway (10755)

ncbi summary :

GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]

uniprot summary :

GIPC1: May be involved in G protein-linked signaling. Belongs to the GIPC family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Vesicle; GAPs, misc.; Motility/polarity/chemotaxis; GAPs. Chromosomal Location of Human Ortholog: 19p13.1. Cellular Component: synaptic vesicle; membrane; endocytic vesicle; cytoplasmic membrane-bound vesicle; cytoplasm; dendritic spine; dendritic shaft; vesicle membrane; cell cortex; cytosol; brush border. Molecular Function: protein binding; protein homodimerization activity; myosin binding; actin binding; receptor binding; PDZ domain binding. Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; synaptic transmission; glutamate secretion; positive regulation of transforming growth factor beta receptor signaling pathway; endothelial cell migration; regulation of protein stability; regulation of synaptic plasticity; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; protein targeting

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage