product summary
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company name :
MyBioSource
product type :
antibody
product name :
FAM109A Antibody (N-term)
catalog :
MBS9207877
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9207877 image 1
FAM109A Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the FAM109A antibody detected the FAM109A protein (arrow).
image 2 :
MyBioSource MBS9207877 image 2
FAM109A Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FAM109A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
product information
catalog number :
MBS9207877
products type :
Antibody
products full name :
FAM109A Antibody (N-term)
products short name :
[FAM109A]
products name syn :
[Sesquipedalian-1; Ses1; 27 kDa inositol polyphosphate phosphatase-interacting protein A; IPIP27A; FAM109A]
other names :
[sesquipedalian-1 isoform 1; Sesquipedalian-1; sesquipedalian-1; family with sequence similarity 109, member A; 27 kDa inositol polyphosphate phosphatase-interacting protein A; IPIP27A]
products gene name :
[FAM109A]
other gene names :
[FAM109A; FAM109A; SES1; IPIP27A; Ses1; IPIP27A]
uniprot entry name :
SESQ1_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human
sequence positions :
[3-31]
sequence length :
262
specificity :
This FAM109A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human FAM109A.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
app notes :
WB~~1:1000. IHC-P~~1:10~50
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info2 :
Function: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. Cellular Location: Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
products description :
This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants.
products references :
Swan, L.E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(8):3511-3516(2010)
ncbi gi num :
295821165
ncbi acc num :
NP_001171467.1
ncbi gb acc num :
NM_001177996.1
uniprot acc num :
Q8N4B1
ncbi mol weight :
27215
ncbi summary :
This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
uniprot summary :
FAM109A: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. Belongs to the sesquipedalian family. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 12q24.12. Cellular Component: recycling endosome; clathrin-coated vesicle; early endosome; trans-Golgi network. Molecular Function: protein binding; protein homodimerization activity. Biological Process: receptor recycling; endosome organization and biogenesis; retrograde transport, endosome to Golgi
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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