MRC1L1 Antibody (N-term) | MyBioSource MBS9207854 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

MRC1L1 Antibody (N-term)

catalog :

MBS9207854

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

more info or order :

MyBioSource product webpage

image

image 1 :

All lanes : Anti-MRC1L1 Antibody (N-term) at 1:2000 dilution. Lane 1: human lung lysates. Lane 2: human spleen lysates. Lane 3: human placenta lysates. Lysates/proteins at 20 ug per lane. Secondary. Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 166 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

image 2 :

MRC1L1 Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the MRC1L1 antibody detected the MRC1L1 protein (arrow).

product information

catalog number :

MBS9207854

products type :

Antibody

products full name :

MRC1L1 Antibody (N-term)

products short name :

[MRC1L1]

products name syn :

[Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206; MRC1; CLEC13D; CLEC13DL; MRC1L1]

other names :

[macrophage mannose receptor 1; Macrophage mannose receptor 1; macrophage mannose receptor 1; mannose receptor, C type 1; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206]

products gene name :

[MRC1]

other gene names :

[MRC1; MRC1; MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; CLEC13D; CLEC13DL; MRC1L1; MMR]

uniprot entry name :

MRC1_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, mouse

sequence length :

1456

specificity :

This MRC1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the N-terminal region of human MRC1L1.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

app notes :

WB~~1:1000

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

other info1 :

. Antigen Region: 359-388 . Calculated MW: 166012

other info2 :

. Cellular location: Endosome membrane; Single -pass type I membrane protein. Cell memabrane; Single-pass type I membrane protein.

products categories :

Crown Antibodies; Immunology

products description :

This gene encodes a type I membrane receptor protein highly related to the mannose receptor C type 1 protein (MRC1). The two genes are located near each other on chromosome 10 in a region thought to represent a segmental duplication.

products references :

Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)

ncbi gi num :

4505245

ncbi acc num :

NP_002429.1

ncbi gb acc num :

NM_002438.3

uniprot acc num :

P22897

ncbi pathways :

Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360); Taurine And Hypotaurine Metabolism Pathway (4360)

ncbi summary :

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]

uniprot summary :

MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc. Chromosomal Location of Human Ortholog: 10p12.33. Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane. Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity. Biological Process: receptor-mediated endocytosis; signal transduction

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage