CMAS Antibody (C-term) | MyBioSource MBS9207740 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CMAS Antibody (C-term)

catalog :

MBS9207740

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

CMAS Antibody (C-term) western blot analysis in U87-MG cell line lysates (35ug/lane).This demonstrates the CMAS antibody detected the CMAS protein (arrow).

product information

catalog number :

MBS9207740

products type :

Antibody

products full name :

CMAS Antibody (C-term)

products short name :

[CMAS]

products name syn :

[N-acylneuraminate cytidylyltransferase; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMAS]

other names :

[N-acylneuraminate cytidylyltransferase; N-acylneuraminate cytidylyltransferase; N-acylneuraminate cytidylyltransferase; cytidine monophosphate N-acetylneuraminic acid synthetase; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase]

products gene name :

[CMAS]

other gene names :

[CMAS; CMAS; CSS; CMP-NeuNAc synthase]

uniprot entry name :

NEUA_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Mouse, Rat)

sequence positions :

[300-327]

sequence length :

434

specificity :

This CMAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the C-terminal region of human CMAS.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

image1 heading :

Western Blot (WB)

other info1 :

Cellular Location: Nucleus. Tissue Location: Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus, and spleen.

products categories :

Crown Antibodies; Metabolism; Signal Transduction

products description :

Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).

products references :

Lawrence S.M., et al. Glycoconj. J. 18:205-213(2001). Bouquin T., et al. Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. Ota T., et al. Nat. Genet. 36:40-45(2004). Bechtel S., et al. BMC Genomics 8:399-399(2007). Bienvenut W.V., et al. Submitted (AUG-2009) to UniProtKB.

ncbi gi num :

8923900

ncbi acc num :

NP_061156.1

ncbi gb acc num :

NM_018686.4

uniprot acc num :

Q8NFW8

ncbi mol weight :

48379

ncbi summary :

Sialic acids are a family of nine-carbon sugars on cell surface glycoproteins and glycolipids that play a pivotal role in determining the structure and function of many animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development and N-glycosylation is a common post-translational modification during cellular differentiation. Sialic acids play important roles in cell-cell communications and immune responses. Sialylated glycoprotein and glycolipid formation requires the activation of a sialic acid to a cytidine monophosphate (CMP) diester by the enzyme encoded by this gene: CMP-N-acetylneuraminic acid synthetase. [provided by RefSeq, Jul 2012]

uniprot summary :

CMAS: Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5 -monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Belongs to the CMP-NeuNAc synthase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.7.7.43; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Transferase. Chromosomal Location of Human Ortholog: 12p12.1. Cellular Component: nucleoplasm; membrane; nucleus. Molecular Function: N-acylneuraminate cytidylyltransferase activity. Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; N-acetylneuraminate metabolic process

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage