PLA2G2D Antibody (C-term) | MyBioSource MBS9207696 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

PLA2G2D Antibody (C-term)

catalog :

MBS9207696

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, flow cytometry, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

PLA2G2D Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PLA2G2D antibody detected the PLA2G2D protein (arrow).

image 2 :

PLA2G2D Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancrease tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLA2G2D Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

image 3 :

PLA2G2D Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9207696

products type :

Antibody

products full name :

PLA2G2D Antibody (C-term)

products short name :

[PLA2G2D]

products name syn :

[Group IID secretory phospholipase A2; GIID sPLA2; sPLA2-IID; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA; stroma-associated homolog; PLA2G2D; SPLASH]

other names :

[group IID secretory phospholipase A2 isoform 2; Group IID secretory phospholipase A2; group IID secretory phospholipase A2; phospholipase A2, group IID; PLA2IID; Phosphatidylcholine 2-acylhydrolase 2D; Secretory-type PLA, stroma-associated homolog]

products gene name :

[PLA2G2D]

other gene names :

[PLA2G2D; PLA2G2D; SPLASH; sPLA2S; PLA2IID; sPLA2-IID; SPLASH; GIID sPLA2; sPLA2-IID]

uniprot entry name :

PA2GD_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence positions :

[105-131]

sequence length :

specificity :

This PLA2G2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-131 amino acids from the C-terminal region of human PLA2G2D.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

WB, IHC-P , FC, E

app notes :

WB~~1:1000. IHC-P~~1:10~50. FC~~1:10~50. Cellular Location: Secreted. Tissue Location: Broadly expressed.

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

image3 heading :

Flow Cytometry (FC/FACS)

other info1 :

Antigen Type: Synthetic Peptide. Function : PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Cellular Location: Secreted. Tissue Location: Broadly expressed.

other info2 :

Antigen Source: HUMAN

products categories :

Cardiovascular; Metabolism; Signal Transduction

products description :

Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

products references :

Davila, S., et al. Genes Immun. 11(3):232-238(2010). Segat, L., et al. Vaccine 28(10):2201-2206(2010). Igarashi, A., et al. Respiration 78(3):312-321(2009). Lessig, J., et al. Asian J. Androl. 10(6):829-836(2008). Lindbom, J., et al. Inflammation 29 (2-3), 108-117 (2005) :

ncbi gi num :

425854812

ncbi acc num :

NP_001258743.1

ncbi gb acc num :

NM_001271814.1

uniprot acc num :

Q9UNK4

ncbi mol weight :

16546

ncbi summary :

This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

uniprot summary :

PLA2G2D: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. Belongs to the phospholipase A2 family. Protein type: Lipid Metabolism - linoleic acid; EC 3.1.1.4; Secreted, signal peptide; Lipid Metabolism - arachidonic acid; Lipid Metabolism - ether lipid; Secreted; Phospholipase; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - alpha-linolenic acid. Chromosomal Location of Human Ortholog: 1p36.12. Cellular Component: extracellular region. Molecular Function: phospholipase A2 activity; calcium ion binding. Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; inflammatory response; lipid catabolic process

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage