STOM Antibody (N-term) | MyBioSource MBS9207690 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

STOM Antibody (N-term)

catalog :

MBS9207690

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of lysates from HepG2, Hela cell line and huamn lung tissue lysate(from left to right), using STOM Antibody (N-term). MBS9207690 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

product information

catalog number :

MBS9207690

products type :

Antibody

products full name :

STOM Antibody (N-term)

products short name :

[STOM]

products name syn :

[Erythrocyte band 7 integral membrane protein; Protein 72b; Stomatin; STOM; BND7; EPB72]

other names :

[erythrocyte band 7 integral membrane protein isoform a; Erythrocyte band 7 integral membrane protein; erythrocyte band 7 integral membrane protein; stomatin; Protein 7.2b; Stomatin]

products gene name :

[STOM]

other gene names :

[STOM; STOM; BND7; EPB7; EPB72; BND7; EPB72]

uniprot entry name :

STOM_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence length :

288

specificity :

This STOM antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human STOM.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

image1 heading :

Western Blot (WB)

other info1 :

Calculated MW: 31731

other info2 :

Function: Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. Celullar location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft Melanosome. Cytoplasmic vesicle {ECO:0000250 UniProtKB:P54116}. Note=Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:12130500). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Tissue location: Detected in erythrocytes (at protein level). Widely expressed

products categories :

Crown Antibodies; Neuroscience

products description :

Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating (By similarity).

products references :

Hiebl-Dirschmied C.M.,et al.Biochim. Biophys. Acta 1090:123-124(1991). Stewart G.W.,et al.Blood 79:1593-1601(1992). Unfried I.,et al.Genomics 30:521-528(1995). Gallagher P.G.,et al.J. Biol. Chem. 270:26358-26363(1995). Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

ncbi gi num :

38016911

ncbi acc num :

NP_004090.4

ncbi gb acc num :

NM_004099.5

uniprot acc num :

P27105

ncbi summary :

This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

uniprot summary :

stomatin: Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating. Belongs to the band 7/mec-2 family. Protein type: Membrane protein, integral; Adaptor/scaffold; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 9q34.1. Cellular Component: extracellular space; cytoskeleton; membrane; mitochondrion; integral to plasma membrane; endoplasmic reticulum; cytoplasm; melanosome; vesicle; lipid raft. Molecular Function: protein homodimerization activity. Biological Process: protein homooligomerization. Disease: Overhydrated Hereditary Stomatocytosis

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage