PRDX6 Antibody (C-term) | MyBioSource MBS9206852 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

PRDX6 Antibody (C-term)

catalog :

MBS9206852

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of PRDX6 Antibody (C-term) in CEM cell line lysates (35ug/lane). PRDX6 (arrow) was detected using the purified Pab.

image 2 :

Western blot analysis of PRDX6 (arrow) using rabbit polyclonal PRDX6 Antibody (C-term) (RB20894). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRDX6 gene (Lane 2).

image 3 :

Formalin-fixed and paraffin-embedded human brain tissue reacted with PRDX6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

product information

catalog number :

MBS9206852

products type :

Antibody

products full name :

PRDX6 Antibody (C-term)

products short name :

[PRDX6]

products name syn :

[Peroxiredoxin-6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2; aiPLA2; 311-; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase; NSGPx; Red blood cells page spot 12; PRDX6; AOP2; KIAA0106]

other names :

[peroxiredoxin-6; Peroxiredoxin-6; peroxiredoxin-6; peroxiredoxin 6; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; Acidic calcium-independent phospholipase A2 (EC:3.1.1.-); aiPLA2; Antioxidant protein 2; Liver 2D page spot 40; Non-selenium glutathione peroxidase (EC:1.11.1.9); NSGPx; Red blood cells page spot 12]

products gene name :

[PRDX6]

other gene names :

[PRDX6; PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m; AOP2; KIAA0106; 1-Cys PRX; aiPLA2; NSGPx]

uniprot entry name :

PRDX6_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Pig, Rat)

sequence positions :

[197-224]

sequence length :

224

specificity :

This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the C-terminal region of human PRDX6.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

concentration :

Vial Concentration: 2

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. IHC-P~~1:50~100. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Flow Cytometry (FC/FACS)

image4 description :

PRDX6 Antibody (C-term) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Cellular Location: Cytoplasm. Lysosome. Cytoplasmic vesicle. Note = Also found in lung secretory organelles.

products categories :

Cancer; Cardiovascular; Cell Biology; Microbiology; Signal Transduction

products description :

PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

products references :

Sorokina,E.M., et.al., Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009). Manevich,Y., et.al., Arch. Biochem. Biophys. 485 (2), 139-149 (2009)

ncbi gi num :

4758638

ncbi acc num :

NP_004896.1

ncbi gb acc num :

NM_004905.2

uniprot acc num :

P30041

ncbi mol weight :

25035

ncbi pathways :

One Carbon Pool By Folate Pathway (9588); One Carbon Pool By Folate Pathway (9588); One Carbon Pool By Folate Pathway (9588); One Carbon Pool By Folate Pathway (9588); One Carbon Pool By Folate Pathway (9588)

ncbi summary :

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

uniprot summary :

PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily. Protein type: EC 1.11.1.15; Amino Acid Metabolism - phenylalanine; Phospholipase; EC 1.11.1.9; Energy Metabolism - methane; Oxidoreductase. Chromosomal Location of Human Ortholog: 1q25.1. Cellular Component: extracellular space; membrane; lysosome; cytoplasmic membrane-bound vesicle; cytoplasm; cytosol. Molecular Function: antioxidant activity; phospholipase A2 activity; protein binding; peroxiredoxin activity; glutathione peroxidase activity. Biological Process: response to reactive oxygen species; hydrogen peroxide catabolic process; phospholipid catabolic process; response to oxidative stress

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage