RBM14 Antibody (C-term) | MyBioSource MBS9206830 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

RBM14 Antibody (C-term)

catalog :

MBS9206830

quantity :

0.08 mL

price :

155 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9206830

products type :

Antibody

products full name :

RBM14 Antibody (C-term)

products short name :

RBM14

products name syn :

RNA-binding protein 14; Paraspeckle protein 2; PSP2; RNA-binding motif protein 14; RRM-containing coactivator activator/modulator; Synaptotagmin-interacting protein; SYT-interacting protein; RBM14; SIP

other names :

RNA-binding protein 14 isoform 2; RNA-binding protein 14; RNA-binding protein 14; RNA binding motif protein 14; Paraspeckle protein 2; PSP2; RNA-binding motif protein 14; RRM-containing coactivator activator/modulator; Synaptotagmin-interacting protein; SYT-interacting protein

products gene name :

RBM14

other gene names :

RBM14; RBM14; SIP; COAA; PSP2; SYTIP1; TMEM137; SIP; PSP2; SYT-interacting protein

uniprot entry name :

RBM14_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Bovine, Mouse)

sequence positions :

563-594

sequence length :

156

specificity :

This RBM14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-594 amino acids from the C-terminal region of human RBM14.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

0.5mg/ml

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. IHC-P~~1:10~50. FC~~1:10~50.

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Function: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Cellular Location: Nucleus. Nucleus, nucleolus. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles. Tissue Location: Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes

products description :

Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.

products references :

Li, X., et al. J. Cell. Biochem. 108(2):378-387(2009). Brooks, Y.S., et al. J. Biol. Chem. 284(27):18033-18046(2009). Kang, Y.K., et al. Cancer Res. 68(19):7887-7896(2008). Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007). Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

ncbi gi num :

311771525

ncbi acc num :

NP_001185765.1

ncbi gb acc num :

NM_001198836.1

uniprot acc num :

Q96PK6

ncbi mol weight :

69492

ncbi summary :

This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]

uniprot summary :

RBM14: an RNA binding protein and transcriptional regulator. Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes. Two alternatively spliced isoforms have been observed. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. Protein type: Nucleolus; RNA-binding; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 11q13.2. Cellular Component: nucleoplasm; transcription factor complex; nucleolus; Srb-mediator complex; ribonucleoprotein complex. Molecular Function: protein binding, bridging; protein binding; ligand-dependent nuclear receptor transcription coactivator activity; RNA binding; nucleotide binding. Biological Process: transcription from RNA polymerase II promoter; estrogen receptor signaling pathway; glucocorticoid receptor signaling pathway; response to hormone stimulus; histone deacetylation; positive regulation of transcription from RNA polymerase II promoter; DNA replication; DNA repair; DNA recombination

size1 :

0.08 mL

price1 :

155 USD

size2 :

0.4 mL

price2 :

340

more info or order :

MyBioSource product webpage