TSPAN7 Antibody (Center) | MyBioSource MBS9206828 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

TSPAN7 Antibody (Center)

catalog :

MBS9206828

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of TSPAN7 Antibody (Center) in CEM cell line lysates (35ug/lane). TSPAN7 (arrow) was detected using the purified Pab.

image 2 :

TSPAN7 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9206828

products type :

Antibody

products full name :

TSPAN7 Antibody (Center)

products short name :

[TSPAN7]

products name syn :

[Tetraspanin-7; Tspan-7; Cell surface glycoprotein A15; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; Transmembrane 4 superfamily member 2; CD231; TSPAN7; A15; DXS1692E; MXS1; TM4SF2]

other names :

[tetraspanin-7; Tetraspanin-7; tetraspanin-7; tetraspanin 7; Cell surface glycoprotein A15; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; Transmembrane 4 superfamily member 2; CD_antigen: CD231]

products gene name :

[TSPAN7]

other gene names :

[TSPAN7; TSPAN7; A15; MXS1; CD231; MRX58; CCG-B7; TM4SF2; TALLA-1; TM4SF2b; DXS1692E; A15; DXS1692E; MXS1; TM4SF2; Tspan-7; TALLA-1]

uniprot entry name :

TSN7_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Mouse)

sequence positions :

[98-124]

sequence length :

249

specificity :

This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C weeks for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Flow Cytometry (FC/FACS)

other info1 :

Calculated MW: 27574

other info2 :

Function: May be involded in cell proliferation and cell motility. Cellular location: Membrane; Multi-pass membrane protein. Tissue location: Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.

products categories :

Signal Transduction

products description :

TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

products references :

Radhakrishnan, Y., et al. Biol. Reprod. 81(4):647-656(2009). Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009). Noor, A., et al. Psychiatr. Genet. 19(3):154-155(2009)

ncbi gi num :

21265104

ncbi acc num :

NP_004606.2

ncbi gb acc num :

NM_004615.3

uniprot acc num :

P41732

ncbi mol weight :

27574

ncbi pathways :

Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway (7102); Ubiquinone And Other Terpenoid-quinone Biosynthesis Pathway (7102)

ncbi summary :

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]

uniprot summary :

TSPAN7: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Defects in TSPAN7 are the cause of mental retardation X- linked type 58 (MRX58). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Protein type: Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: Xp11.4. Cellular Component: integral to plasma membrane. Biological Process: viral reproduction. Disease: Mental Retardation, X-linked 58

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage