GPM6B Antibody (N-term) | MyBioSource MBS9206791 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

GPM6B Antibody (N-term)

catalog :

MBS9206791

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

GPM6B Antibody (N-term) western blot analysis in ZR-75-1,CEM cell line lysates (35ug/lane).This demonstrates the GPM6B antibody detected the GPM6B protein (arrow).

image 2 :

GPM6B Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9206791

products type :

Antibody

products full name :

GPM6B Antibody (N-term)

products short name :

[GPM6B]

products name syn :

[Neuronal membrane glycoprotein M6-b; M6b; GPM6B; M6B]

other names :

[neuronal membrane glycoprotein M6-b isoform 4; Neuronal membrane glycoprotein M6-b; neuronal membrane glycoprotein M6-b; glycoprotein M6B]

products gene name :

[GPM6B]

other gene names :

[GPM6B; GPM6B; M6B; M6B; M6b]

uniprot entry name :

GPM6B_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human (Predicted Reactivity: Rat)

sequence positions :

[1-30]

sequence length :

246

specificity :

This GPM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GPM6B.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.27

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)

app notes :

WB~~1:1000. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Flow Cytometry (FC/FACS)

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Function: May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. Cellular Location: Cell membrane; Multi-pass membrane protein. Note=Colocalizes with SERT at the plasma membrane. Tissue Location: Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia

products categories :

Developmental Biology; Neuroscience

products description :

This gene encodes a membrane glycoprotein that belongs to. the proteolipid protein family. Proteolipid protein family members. are expressed in most brain regions and are thought to be involved. in cellular housekeeping functions, such as membrane trafficking. and cell-to-cell communication.

products references :

Fjorback, A.W., et al. J. Mol. Neurosci. 37(3):191-200(2009). Sebastiani, P., et al. Am. J. Hematol. 83(3):189-195(2008). Combes, P., et al. Neurogenetics 7(1):31-37(2006). Henneke, M., et al. Am. J. Med. Genet. A 128A (2), 156-158 (2004) :. Werner, H., et al. Mol. Cell. Neurosci. 18(6):593-605(2001)

ncbi gi num :

50263053

ncbi acc num :

NP_001001994.1

ncbi gb acc num :

NM_001001994.1

uniprot acc num :

Q13491

ncbi mol weight :

28989

ncbi summary :

This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions, such as membrane trafficking and cell-to-cell communication. [provided by RefSeq, Apr 2009]

uniprot summary :

GPM6B: May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. Belongs to the myelin proteolipid protein family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: Xp22.2. Cellular Component: integral to membrane; plasma membrane; lipid raft. Biological Process: negative regulation of serotonin uptake; nervous system development; protein transport; ossification; regulation of actin cytoskeleton organization and biogenesis; regulation of focal adhesion formation; cell differentiation; positive regulation of bone mineralization

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage