product summary
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company name :
MyBioSource
product type :
antibody
product name :
Phospho-CLDN2 (Y224) Antibody
catalog :
MBS9206165
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, enzyme immunoassay, dot blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9206165 image 1
Dot blot analysis of anti-Phospho-CLDN2-pY224 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
product information
catalog number :
MBS9206165
products type :
Antibody
products full name :
Phospho-CLDN2 (Y224) Antibody
products short name :
[Phospho-CLDN2 (Y224)]
products name syn :
[Claudin-2; SP82; CLDN2]
other names :
[claudin-2; Claudin-2; claudin-2; claudin 2; SP82]
products gene name :
[CLDN2]
other gene names :
[CLDN2; CLDN2]
uniprot entry name :
CLD2_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human
sequence length :
230
specificity :
This CLDN2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y224 of human CLDN2.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Dot Blot (DB), ELISA (EIA)
app notes :
DB~~1:500
image1 heading :
Dot Blot (DB)
other info1 :
Calculated MW: 24549
other info2 :
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Cellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
products categories :
Signal Transduction; Phospho Antibodies
products description :
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions.
products references :
Morita,K., Proc. Natl. Acad. Sci. U.S.A. 96 (2), 511-516 (1999). Furuse,M., J. Cell Biol. 141 (7), 1539-1550 (1998)
ncbi gi num :
283806628
ncbi acc num :
NP_001164563.1
ncbi gb acc num :
NM_001171092.1
uniprot acc num :
P57739
ncbi pathways :
Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075); Starch And Sucrose Metabolism Pathway (9075)
ncbi summary :
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
uniprot summary :
Claudin-2: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. Protein type: Membrane protein, integral; Cytoskeletal; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: Xq22.3-q23. Cellular Component: tight junction; plasma membrane; integral to membrane. Molecular Function: identical protein binding; structural molecule activity. Biological Process: calcium-independent cell-cell adhesion
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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