catalog number :
MBS9205364
products full name :
TCRB Antibody (Center)
products short name :
[TCRB]
products name syn :
[T-cell receptor beta chain V region CTL-L17; TCRB]
other names :
[T-cell receptor beta chain V region CTL-L17; T-cell receptor beta chain V region CTL-L17]
products gene name :
[TCRB]
other gene names :
[TCRB]
uniprot entry name :
TVB2_HUMAN
sequence positions :
[67-94]
specificity :
This TCRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human TCRB.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Western Blot (WB)
image4 heading :
Western Blot (WB)
image4 description :
TCRB Antibody (Center) western blot analysis in MDA-MB231,HEK293,Ramos,NCI-H460 cell line lysates (35ug/lane).This demonstrates the TCRB antibody detected the TCRB protein (arrow).
image5 heading :
Western Blot (WB)
image5 description :
Anti-TCRB Antibody (Center) at 1:2000 dilution + Jurkat whole cell lysate Lysates/proteins at 20ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 15 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
products categories :
Immunology
products description :
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
uniprot summary :
TCRB: . Protein type: Receptor, misc. Chromosomal Location of Human Ortholog: 7q34