product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Jak1 Antibody (N-term)
catalog :
MBS9205000
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Mouse Jak1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Jak1 antibody detected the Jak1 protein (arrow).
product information
catalog number :
MBS9205000
products type :
Antibody
products full name :
Mouse Jak1 Antibody (N-term)
products short name :
[Jak1]
products name syn :
[Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1; Jak1]
other names :
[Tyrosine-protein kinase JAK1; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1]
products gene name :
[Jak1]
other gene names :
[Jak1; JAK-1]
uniprot entry name :
JAK1_MOUSE
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Mouse
sequence positions :
[120-148]
sequence length :
1,153
specificity :
This Mouse Jak1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the N-terminal region of mouse Jak1.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
concentration :
Vial Concentration: 0.5
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weekss. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB~~1:1000
image1 heading :
Western Blot (WB)
other info1 :
Antigen Type: Synthetic Peptide
other info2 :
Antigen Source: MOUSE. Function: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin(IL)-2 receptor. Cellular Location: Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated
products categories :
Cancer; Developmental Biology
products description :
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
ncbi gi num :
1708580
ncbi acc num :
P52332.1
uniprot acc num :
P52332
ncbi mol weight :
133367
uniprot summary :
JAK1: a widely expressed non-receptor tyrosine-kinase involved in the interferon-alpha/beta and -gamma signal transduction pathways. Couples cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. A selective Jak1 inhibitor induces apoptosis in NRP-154 prostate cancer cell line. A single mutation seen in tyrosine kinome screen of colon cancers. Activated in B cell lines from patients with post-transplant lymphoproliferative disorder, and in a mouse Lck-driven T cell lymphoma. Inhibitor: Piceatannol. Protein type: Protein kinase, TK; Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; JakA family. Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; focal adhesion; membrane; cytoplasm; intracellular; nucleus. Molecular Function: transferase activity; protein binding; growth hormone receptor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; protein phosphatase binding; ATP binding; protein kinase activity; CCR5 chemokine receptor binding. Biological Process: response to antibiotic; cell migration; peptidyl-tyrosine phosphorylation; cytokine and chemokine mediated signaling pathway; protein amino acid autophosphorylation; innate immune response; cell differentiation; protein amino acid phosphorylation; enzyme linked receptor protein signaling pathway; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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