catalog number :
MBS9204980
products full name :
B7H6 Antibody (C-term)
products short name :
[B7H6]
products name syn :
[Natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; B7-H6; NCR3LG1; B7H6]
other names :
[natural cytotoxicity triggering receptor 3 ligand 1; Natural cytotoxicity triggering receptor 3 ligand 1; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; B7 homolog 6; B7-H6]
products gene name :
[NCR3LG1]
other gene names :
[NCR3LG1; NCR3LG1; B7H6; B7-H6; DKFZp686O24166; B7H6; B7-H6]
uniprot entry name :
NR3L1_HUMAN
sequence positions :
[389-415]
specificity :
This B7H6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-415 amino acids from the C-terminal region of human B7H6.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
other info1 :
Cellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Location: Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B-lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level)
products categories :
Immunology
products description :
Triggers NCR3-dependent natural killer cell activation.
ncbi acc num :
NP_001189368.1
ncbi gb acc num :
NM_001202439.2
ncbi summary :
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
uniprot summary :
B7-H6: Triggers NCR3-dependent natural killer cell activation. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 11p15.1. Cellular Component: plasma membrane; integral to membrane; viral capsid. Molecular Function: structural molecule activity