VAMP3 Antibody (Center) | MyBioSource MBS9204928 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

VAMP3 Antibody (Center)

catalog :

MBS9204928

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, zebrafish

application :

western blot, ELISA, enzyme immunoassay, immunohistochemistry - paraffin section

more info or order :

MyBioSource product webpage

image

image 1 :

VAMP3 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).

image 2 :

VAMP3 Antibody (Center) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).

image 3 :

VAMP3 Antibody (Center) (MBS9204928)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VAMP3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

product information

catalog number :

MBS9204928

products type :

Antibody

products full name :

VAMP3 Antibody (Center)

products short name :

[VAMP3]

products name syn :

[Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptobrevin-3; VAMP3; SYB3]

other names :

[vesicle-associated membrane protein 3; Vesicle-associated membrane protein 3; vesicle-associated membrane protein 3; vesicle-associated membrane protein 3; Cellubrevin; CEB; Synaptobrevin-3]

products gene name :

[VAMP3]

other gene names :

[VAMP3; VAMP3; CEB; SYB3; VAMP-3; CEB]

uniprot entry name :

VAMP3_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human, Mouse, Zebrafish (Predicted Reactivity: Bovine, Rat, Monkey)

sequence positions :

[15-43]

sequence length :

100

specificity :

This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)

app notes :

WB~~1:1000!!IHC-P~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

other info1 :

Antigen Type: Synthetic Peptide. Primary Accession: Q15836. Other Accession: P63025, P63024, Q4R8T0, Q2KJD2, P63045, P63044, P63027, P63026, Q63666, Q62442, P23763, Q0V7N0, NP_004772.1. Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Cellular Location: Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome

other info2 :

Antigen Source: HUMAN

products categories :

Cancer; Metabolism; Neuroscience; Signal Transduction

products description :

Synaptobrevins/VAMPs, syntaxins, and the 25-kD. synaptosomal-associated protein are the main components of a. protein complex involved in the docking and/or fusion of synaptic. vesicles with the presynaptic membrane. This gene is a member of. the vesicle-associated membrane protein (VAMP)/synaptobrevin. family. Because of its high homology to other known VAMPs, its. broad tissue distribution, and its subcellular localization, the. protein encoded by this gene was shown to be the human equivalent. of the rodent cellubrevin. In platelets the protein resides on a. compartment that is not mobilized to the plasma membrane on calcium. or thrombin stimulation.

products references :

Ban, H.J., et al. BMC Genet. 11, 26 (2010) :. Fader, C.M., et al. Biochim. Biophys. Acta 1793(12):1901-1916(2009). Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :. Vassilopoulos, S., et al. Science 324(5931):1192-1196(2009). Luftman, K., et al. Biochem. Biophys. Res. Commun. 380(1):65-70(2009)

ncbi gi num :

4759300

ncbi acc num :

NP_004772.1

ncbi gb acc num :

NM_004781.3

uniprot acc num :

Q15836

ncbi mol weight :

11309

ncbi pathways :

Base Excision Repair Pathway (9341); Base Excision Repair Pathway (9341); Base Excision Repair Pathway (9341); Base Excision Repair Pathway (9341); Base Excision Repair Pathway (9341)

ncbi summary :

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]

uniprot summary :

VAMP3: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Belongs to the synaptobrevin family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1p36.23. Cellular Component: neuron projection; cell surface; clathrin-coated vesicle; intracellular membrane-bound organelle; integral to membrane; clathrin coated vesicle membrane; cytosol; secretory granule; SNARE complex; recycling endosome; synaptic vesicle; apical plasma membrane; plasma membrane; intracellular; cell junction. Molecular Function: SNAP receptor activity; protein binding; SNARE binding; syntaxin-1 binding. Biological Process: vesicle-mediated transport; vesicle fusion; exocytosis; neurotransmitter secretion; Golgi to plasma membrane protein transport; protein complex assembly; positive regulation of immunoglobulin secretion; retrograde transport, endosome to Golgi; positive regulation of receptor recycling; vesicle docking during exocytosis; calcium ion-dependent exocytosis

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage