Mouse Srms Antibody (Center) | MyBioSource MBS9204466 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse Srms Antibody (Center)

catalog :

MBS9204466

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabilized mouse skin tissue labeling Pdx1 with MBS9204466 at 1/25 dilution, followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG (1583138) secondary antibody at 1/400 dilution (green). Confocal image showing cytoplasm staining on mouse skin tissue. The nuclear counter stain is DAPI (blue).

image 2 :

Anti-Srms Antibody (C-term) at 1:2000 dilution + mouse liver lysates. Lysates/proteins at 20 ug per lane. Secondary. Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 56 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

image 3 :

Western blot analysis of lysates from mouse liver, mouse spleen tissue lysate (from left to right), using Srms Antibody (Center). MBS9204466 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

product information

catalog number :

MBS9204466

products type :

Antibody

products full name :

Mouse Srms Antibody (Center)

products short name :

[Srms]

products name syn :

[Tyrosine-protein kinase Srms; PTK70; Srms; Srm]

other names :

[Tyrosine-protein kinase Srms; Tyrosine-protein kinase Srms; tyrosine-protein kinase Srms; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; PTK70]

products gene name :

[Srms]

other gene names :

[Srms; Srms; srm; A230069J08Rik; Srm]

uniprot entry name :

SRMS_MOUSE

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Mouse

sequence length :

496

specificity :

This Mouse Srms antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 113-147 amino acids from the Central region of Mouse Srms.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)

app notes :

IF~~1:25. WB~~1:1000

image1 heading :

Immunofluorescent

image2 heading :

Western Blot (WB)

image3 heading :

Western Blot (WB)

other info1 :

Crown Antibody: Yes

other info2 :

Antigen Source: HUMAN. Function: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. May be involved in proliferation or differentiation of keratinocytes in the skin. Function: Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent. Cellular Location: Cytoplasm {ECO:0000250 UniProtKB:Q9H3Y6}. Note=Localizes to punctate cytoplasmic structures {ECO:0000250 UniProtKB:Q9H3Y6}. Tissue Location: Higher expression in liver, lung, thymus and skin than in brain, kidney, heart and spleen (PubMed:9226137). In skin, highly expressed in keratinocytes (PubMed:9226137). Abundant in lung, liver, spleen, kidney and testis and is also detected in the cerebrum (PubMed:7935409).

products categories :

Crown Antibodies; Signal Transduction

products description :

Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. May be involved in proliferation or differentiation of keratinocytes in the skin.

products references :

Kawachi Y.,et al.Exp. Dermatol. 6:140-146(1997). Kohmura N.,et al.Mol. Cell. Biol. 14:6915-6925(1994). Wall M.,et al.Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.

ncbi gi num :

27808677

ncbi acc num :

Q62270.2

uniprot acc num :

Q62270

ncbi mol weight :

55758

ncbi pathways :

Base Excision Repair Pathway (20811)

uniprot summary :

SRMS: a tyrosine kinase of the Src family. Protein type: Protein kinase, tyrosine (non-receptor); Motility/polarity/chemotaxis; Protein kinase, TK; Kinase, protein; EC 2.7.10.2; TK group; Src family. Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm. Molecular Function: transferase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; kinase activity; ATP binding; protein kinase activity; receptor binding. Biological Process: cell migration; innate immune response; actin cytoskeleton organization and biogenesis; cell differentiation; protein amino acid phosphorylation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage