catalog number :
MBS9203899
products full name :
BACH2 Antibody (C-term)
products short name :
[BACH2]
products name syn :
[Transcription regulator protein BACH2; BTB and CNC homolog 2; BACH2]
other names :
[transcription regulator protein BACH2; Transcription regulator protein BACH2; transcription regulator protein BACH2; BTB and CNC homology 1, basic leucine zipper transcription factor 2; BTB and CNC homolog 2]
products gene name :
[BACH2]
other gene names :
[BACH2; BACH2; BTBD25]
uniprot entry name :
BACH2_HUMAN
specificity :
This BACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 815-841 amino acids from the C-terminal region of human BACH2.
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Flow Cytometry (FC), Western Blot (WB), ELISA (EIA)
app notes :
FC~~1:10~50. WB~~1:2000
image1 heading :
Testing Data
image2 heading :
Testing Data
image3 heading :
Testing Data
other info1 :
Antigen Region: 815-841. Tissue Location: B-cell specific. Cellular Location: Cytoplasm. Nucleus; Note: Nucleocytoplasmic shuttling is controlled by phosphorylation. Function: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin (By similarity).
products categories :
Cell Biology; Immunology; Metabolism
products references :
Hinks, A., et al. Ann. Rheum. Dis. (2010) In press :. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :. Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010). Pierce, B.L., et al. Hum. Hered. 69(3):193-201(2010). Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
ncbi acc num :
NP_001164265.1
ncbi gb acc num :
NM_001170794.1
uniprot summary :
BACH2: Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK. Belongs to the bZIP family. CNC subfamily. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 6q15. Cellular Component: cytoplasm; nucleus. Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter