(Mouse) Epcam Antibody (C-term) | MyBioSource MBS9202620 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

(Mouse) Epcam Antibody (C-term)

catalog :

MBS9202620

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, ELISA, flow cytometry, FACS

more info or order :

MyBioSource product webpage

image

image 1 :

Flow cytometric analysis of HepG2 cells using (Mouse) Epcam Antibody (C-term)(green) compared to an isotype control of rabbit IgG(blue). MBS9202620 was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.

image 2 :

Western blot analysis of lysates from mouse kidney, mouse lung, mouse testis tissue lysate (from left to right), using Epcam Antibody (C-term). MBS9202620 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

product information

catalog number :

MBS9202620

products type :

Antibody

products full name :

(Mouse) Epcam Antibody (C-term)

products short name :

[Epcam]

products name syn :

[Epithelial cell adhesion molecule; Ep-CAM; Epithelial glycoprotein 314; EGP314; mEGP314; Protein 289A; Tumor-associated calcium signal transducer 1; CD326; Epcam; Tacstd1]

other names :

[epithelial cell adhesion molecule; Epithelial cell adhesion molecule; epithelial cell adhesion molecule; epithelial cell adhesion molecule; Epithelial glycoprotein 314; EGP314; mEGP314; Protein 289A; Tumor-associated calcium signal transducer 1; CD_antigen: CD326]

products gene name :

[Epcam]

other gene names :

[Epcam; Epcam; EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1; Tacstd1; Ep-CAM; EGP314; mEGP314]

uniprot entry name :

EPCAM_MOUSE

clonality :

Polyclonal

isotype :

Rabbit IgG

host :

Rabbit

reactivity :

Mouse (Predicted Reactivity: Rat)

sequence length :

315

specificity :

This Mouse Epcam antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 302-335 amino acids from the C-terminal region of mouse Epcam.

purity :

Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a Protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Flow Cytometry (FC/FACS), Western Blot (WB), ELISA

app notes :

FC~~1:25. WB~~1:1000

image1 heading :

Flow Cytometry (FC/FACS)

image2 heading :

Western Blot (WB)

other info1 :

Cellular Location: Lateral cell membrane{ECO:0000250 UniProtKB:P16422};Single-pass type I membrane protein{ECO:0000250 UniProtKB:P16422}. Cell junction, tight junction{ECO:0000250 UniProtKB:P16422}. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction{ECO:0000250 UniProtKB:P16422}

products categories :

Crown Antibodies

products description :

May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).

products references :

Bergsagel P.L.,et al.J. Immunol. 148:590-596(1992). Carninci P.,et al.Science 309:1559-1563(2005).

ncbi gi num :

112293275

ncbi acc num :

NP_032558.2

ncbi gb acc num :

NM_008532.2

uniprot acc num :

Q99JW5

uniprot summary :

EPCAM: a single-pass type I membrane protein of the EPCAM family. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas including pancreatic carcinoma. May be a marker of cancer stem cells. Protein type: Membrane protein, integral; Motility/polarity/chemotaxis. Cellular Component: tight junction; cell surface; membrane; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; cell junction; lateral plasma membrane. Molecular Function: protein complex binding. Biological Process: positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation; negative regulation of apoptosis

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage