ND3 Antibody (N-term) | MyBioSource MBS9202094 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

ND3 Antibody (N-term)

catalog :

MBS9202094

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, flow cytometry, FACS, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis of lysate from K562 cell line, using ND3 Antibody (N-term). MBS9202094 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

image 2 :

ND3 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

product information

catalog number :

MBS9202094

products type :

Antibody

products full name :

ND3 Antibody (N-term)

products short name :

[ND3]

products name syn :

[NADH-ubiquinone oxidoreductase chain 3; NADH dehydrogenase subunit 3; MT-ND3; MTND3; NADH3; ND3]

other names :

[NADH dehydrogenase subunit 3 (mitochondrion); NADH-ubiquinone oxidoreductase chain 3; NADH dehydrogenase, subunit 3 (complex I); mitochondrially encoded NADH dehydrogenase 3; NADH dehydrogenase subunit 3]

products gene name :

[MT-ND3]

other gene names :

[MT-ND3; MT-ND3; MTND3; ND3; MTND3; NADH3; ND3]

uniprot entry name :

NU3M_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence positions :

[10-38]

sequence length :

115

specificity :

This ND3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human ND3.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB)

app notes :

WB~~1:1000. FC~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Flow Cytometry (FC/FACS)

other info1 :

Calculated MW: 13186

other info2 :

Cellular location: Mitochondrion membrane; Multi-pass membrane protein.

products categories :

Metabolism; Signal Transduction

products description :

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

ncbi gi num :

251831114

ncbi acc num :

YP_003024033.1

ncbi gb acc num :

NC_012920.1

uniprot acc num :

P03897

ncbi pathways :

Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537); Citrate Cycle (TCA Cycle) Pathway (4537)

uniprot summary :

MT-ND3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND3 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions. Defects in MT-ND3 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Belongs to the complex I subunit 3 family. Protein type: Mitochondrial; Oxidoreductase; Membrane protein, multi-pass; Membrane protein, integral; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation. Chromosomal Location of Human Ortholog: -

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage