PTDSS2 Antibody (N-term) | MyBioSource MBS9201929 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

PTDSS2 Antibody (N-term)

catalog :

MBS9201929

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

PTDSS2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PTDSS2 antibody detected the PTDSS2 protein (arrow).

image 2 :

PTDSS2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTDSS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

product information

catalog number :

MBS9201929

products type :

Antibody

products full name :

PTDSS2 Antibody (N-term)

products short name :

[PTDSS2]

products name syn :

[Phosphatidylserine synthase 2; PSS-2; PtdSer synthase 2; Serine-exchange enzyme II; PTDSS2; PSS2]

other names :

[phosphatidylserine synthase 2; Phosphatidylserine synthase 2; phosphatidylserine synthase 2; phosphatidylserine synthase 2; Serine-exchange enzyme II]

products gene name :

[PTDSS2]

other gene names :

[PTDSS2; PTDSS2; PSS2; PSS2; PSS-2; PtdSer synthase 2]

uniprot entry name :

PTSS2_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence positions :

[1-30]

sequence length :

487

specificity :

This PTDSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTDSS2.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.3

storage stability :

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)

app notes :

WB~~1:1000. IHC-P~~1:10~50

image1 heading :

Western Blot (WB)

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Antigen Type: Synthetic Peptide. Function: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Highly enriched in the mitochondria-associated membrane (MAM).

other info2 :

Antigen Source: HUMAN

products categories :

Metabolism; Signal Transduction

products description :

Phosphatidylserine (PS) accounts for 5 to 10% of cell. membrane phospholipids. In addition to its role as a structural. component, PS is involved in cell signaling, blood coagulation, and. apoptosis. PS is synthesized by a calcium-dependent base-exchange. reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that. exchange L-serine for the polar head group of phosphatidylcholine. (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al.,. 2001 [PubMed 11084049]).

products references :

Tomohiro, S., et al. Biochem. J. 418(2):421-429(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Olsen, J.V., et al. Cell 127(3):635-648(2006). Grandmaison, P.A., et al. Biochim. Biophys. Acta 1636(1):1-11(2004). Sturbois-Balcerzak, B., et al. J. Biol. Chem. 276(11):8205-8212(2001)

ncbi gi num :

13540555

ncbi acc num :

NP_110410.1

ncbi gb acc num :

NM_030783.1

uniprot acc num :

Q9BVG9

ncbi mol weight :

56253

ncbi pathways :

, Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490); , Pathway (81490)

ncbi summary :

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009]

uniprot summary :

PTDSS2: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Belongs to the phosphatidyl serine synthase family. Protein type: Lipid Metabolism - glycerophospholipid; EC 2.7.8.29; Membrane protein, multi-pass; Transferase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane. Molecular Function: CDP-diacylglycerol-serine O-phosphatidyltransferase activity. Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylserine biosynthetic process

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage