SLC30A10 Antibody (C-term) | MyBioSource MBS9201799 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

SLC30A10 Antibody (C-term)

catalog :

MBS9201799

quantity :

0.08 mL

price :

165 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

SLC30A10 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SLC30A10 antibody detected the SLC30A10 protein (arrow).

image 2 :

Anti-SLC30A10 Antibody (C-term) at 1:2000 dilution + human liver lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 53 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

image 3 :

All lanes : Anti-SLC30A10 Antibody (C-term) at 1:2000 dilution Lane 1: human fetal brain lysate Lane 2: human fetal liver lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 53 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

product information

catalog number :

MBS9201799

products type :

Antibody

products full name :

SLC30A10 Antibody (C-term)

products short name :

[SLC30A10]

products name syn :

[Zinc transporter 10; ZnT-10; Solute carrier family 30 member 10; SLC30A10; ZNT10; ZNT8]

other names :

[zinc transporter 10; Zinc transporter 10; zinc transporter 10; solute carrier family 30, member 10; Solute carrier family 30 member 10]

products gene name :

[SLC30A10]

other gene names :

[SLC30A10; SLC30A10; ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; ZNT10; ZNT8; ZnT-10]

uniprot entry name :

ZNT10_HUMAN

clonality :

Polyclonal

isotype :

Rabbit Ig

host :

Rabbit

reactivity :

Human

sequence positions :

[331-359]

sequence length :

485

specificity :

This SLC30A10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the C-terminal region of human SLC30A10.

purity :

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

form :

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

concentration :

Vial Concentration: 0.5

storage stability :

Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

tested application :

Western Blot (WB), ELISA (EIA)

app notes :

WB~~1:1000

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot

image3 heading :

Western Blot

other info1 :

Antigen Type: Synthetic Peptide

other info2 :

Antigen Source: HUMAN. Function: Plays a pivotal role in manganese transp ort. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Cellular Location: Cell membrane; Multi-pass membrane protein. Tissue Location: Specifically expressed in fetal liver and fetal brain.

products categories :

Signal Transduction

products description :

Zinc functions as a cofactor for numerous enzymes, nuclear. factors, and hormones and as an intra- and intercellular signal. ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the. cation diffusion facilitator family, such as SLC30A10, permit. cellular efflux of zinc (Seve et al., 2004 [PubMed. 15154973]).

products references :

Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008). Seve, M., et al. BMC Genomics 5 (1), 32 (2004) :

ncbi gi num :

52351208

ncbi acc num :

NP_061183.2

ncbi gb acc num :

NM_018713.2

uniprot acc num :

Q6XR72

ncbi mol weight :

52684

ncbi summary :

This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]

uniprot summary :

SLC30A10: May be involved in zinc transport out of the cell, being a zinc-efflux transporter. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 1q41. Cellular Component: integral to membrane; plasma membrane. Molecular Function: cation transmembrane transporter activity. Biological Process: manganese ion transport; zinc ion transport. Disease: Hypermanganesemia With Dystonia, Polycythemia, And Cirrhosis

size1 :

0.08 mL

price1 :

165 USD

size2 :

0.4 mL

price2 :

370

more info or order :

MyBioSource product webpage