catalog number :
MBS9201717
products full name :
PLVAP Antibody (Center)
products short name :
[PLVAP]
products name syn :
[Plasmalemma vesicle-associated protein; Fenestrated endothelial-linked structure protein; Plasmalemma vesicle protein 1; PV-1; PLVAP; FELS; PV1]
other names :
[plasmalemma vesicle-associated protein; Plasmalemma vesicle-associated protein; plasmalemma vesicle-associated protein; plasmalemma vesicle associated protein; Fenestrated endothelial-linked structure protein; Plasmalemma vesicle protein 1; PV-1]
products gene name :
[PLVAP]
other gene names :
[PLVAP; PLVAP; PV1; FELS; PV-1; gp68; FELS; PV1; PV-1]
uniprot entry name :
PLVAP_HUMAN
sequence positions :
[214-242]
specificity :
This PLVAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human PLVAP.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 Weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
app notes :
WB~~1:1000. FC~~1:10~50
image1 heading :
Western Blot (WB)
image2 heading :
Flow Cytometry (FC/FACS)
other info1 :
Antigen Type: Synthetic Peptide. Function: Involved in the formulation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability
products categories :
Signal Transduction
products description :
PLVAP involved in the formation of stomatal and fenestral diaphragms of caveolae. This protein may function in microvascular permeability.
products references :
Keuschnigg, J., et al. Blood 114(2):478-484(2009). Carson-Walter, E.B., et al. Clin. Cancer Res. 11(21):7643-7650(2005). Strickland, L.A., et al. J. Pathol. 206(4):466-475(2005). Stan, R.V., et al. Mol. Biol. Cell 15(8):3615-3630(2004). Hnasko, R., et al. J. Endocrinol. 175(3):649-661(2002). Stan, R.V., et al. Genomics 72(3):304-313(2001). Stan, R.V., et al. J. Cell Biol. 145(6):1189-1198(1999)
ncbi acc num :
NP_112600.1
ncbi gb acc num :
NM_031310.2
uniprot summary :
PLVAP: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability. Protein type: Membrane protein, integral; Cell surface. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: cell surface; perinuclear region of cytoplasm; integral to membrane; caveola. Molecular Function: protein binding; protein homodimerization activity. Biological Process: positive regulation of cellular extravasation; tumor necrosis factor-mediated signaling pathway; MAPKKK cascade