catalog number :
MBS9201462
products full name :
NPFFR1 Antibody (C-term)
products short name :
[NPFFR1]
products name syn :
[Neuropeptide FF receptor 1; G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022; NPFFR1; GPR147; NPFF1]
other names :
[neuropeptide FF receptor 1; Neuropeptide FF receptor 1; neuropeptide FF receptor 1; neuropeptide FF receptor 1; G-protein coupled receptor 147; RFamide-related peptide receptor OT7T022]
products gene name :
[NPFFR1]
other gene names :
[NPFFR1; NPFFR1; NPFF1; GPR147; NPFF1R1; OT7T022; GPR147; NPFF1]
uniprot entry name :
NPFF1_HUMAN
sequence positions :
[337-366]
specificity :
This NPFFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human NPFFR1.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
storage stability :
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
image1 heading :
Western Blot (WB)
other info1 :
Calculated MW: 47819. Cellular location: Cell membrane; Multi-pass membraneprotein.
other info2 :
Function: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system.
products categories :
Neuroscience; Signal Transduction; GPCR Antibodies
products description :
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
products references :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :. Ubuka, T., et al. PLoS ONE 4 (12), E8400 (2009) :. Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006). Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006). Bonini, J.A., et al. J. Biol. Chem. 275(50):39324-39331(2000)
ncbi acc num :
NP_071429.1
ncbi gb acc num :
NM_022146.4
uniprot summary :
NPFFR1: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 10q21-q22. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; neuropeptide receptor activity; peptide binding. Biological Process: synaptic transmission; neuropeptide signaling pathway; cellular response to hormone stimulus