product summary
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company name :
MyBioSource
product type :
antibody
product name :
CLDN12 Antibody (N-term)
catalog :
MBS9200967
quantity :
0.08 mL
price :
165 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, flow cytometry, FACS, enzyme immunoassay
more info or order :
image
image 1 :
CLDN12 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CLDN12 antibody detected the CLDN12 protein (arrow).
image 2 :
CLDN12 Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
product information
catalog number :
MBS9200967
products type :
Antibody
products full name :
CLDN12 Antibody (N-term)
products short name :
[CLDN12]
products name syn :
[Claudin-12; CLDN12]
other names :
[claudin-12; Claudin-12; claudin-12; claudin 12]
products gene name :
[CLDN12]
other gene names :
[CLDN12; CLDN12]
uniprot entry name :
CLD12_HUMAN
clonality :
Polyclonal
isotype :
Rabbit Ig
host :
Rabbit
reactivity :
Human (Predicted Reactivity: Bovine, Mouse)
sequence positions :
[19-46]
sequence length :
244
specificity :
This CLDN12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-46 amino acids from the N-terminal region of human CLDN12.
purity :
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
form :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
concentration :
Vial Concentration: 0.43 mg/ml
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS)
app notes :
WB~~1:1000. FC~~1:10~50
image1 heading :
Western Blot (WB)
image2 heading :
Flow Cytometry (FC/FACS)
other info1 :
Antigen Type: Synthetic Peptide. Clone Names: RB22446. Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Cellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
other info2 :
Antigen Source: HUMAN
products categories :
Signal Transduction
ncbi gi num :
297374758
ncbi acc num :
NP_001172001.1
ncbi gb acc num :
NM_001185072.2
uniprot acc num :
P56749
ncbi mol weight :
27110
ncbi pathways :
Phosphonate And Phosphinate Metabolism Pathway (9069); Phosphonate And Phosphinate Metabolism Pathway (9069); Phosphonate And Phosphinate Metabolism Pathway (9069); Phosphonate And Phosphinate Metabolism Pathway (9069)
ncbi summary :
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
uniprot summary :
Claudin-12: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 7q21. Cellular Component: tight junction; integral to membrane; lateral plasma membrane. Molecular Function: identical protein binding; structural molecule activity. Biological Process: intercellular junction assembly and maintenance; calcium-independent cell-cell adhesion
size1 :
0.08 mL
price1 :
165 USD
size2 :
0.4 mL
price2 :
370
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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