product summary
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company name :
MyBioSource
product type :
antibody
product name :
HAGH Antibody (C-term) (Ascites)
catalog :
MBS9200592
quantity :
0.1 mL
price :
370 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[611CT23.6.1]
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9200592 image 1
HAGH Antibody (C-term)(Ascites) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HAGH antibody detected the HAGH protein (arrow).
product information
catalog number :
MBS9200592
products type :
Antibody
products full name :
HAGH Antibody (C-term) (Ascites)
products short name :
[HAGH]
products name syn :
[Hydroxyacylglutathione hydrolase; mitochondrial; Glyoxalase II; Glx II; HAGH; GLO2; HAGH1]
other names :
[hydroxyacylglutathione hydrolase, mitochondrial isoform 2; Hydroxyacylglutathione hydrolase, mitochondrial; hydroxyacylglutathione hydrolase, mitochondrial; hydroxyacylglutathione hydrolase; Glyoxalase II; Glx II]
products gene name :
[HAGH]
other gene names :
[HAGH; HAGH; GLO2; GLX2; GLXII; HAGH1; GLO2; HAGH1; Glx II]
uniprot entry name :
GLO2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
[611CT23.6.1]
host :
Mouse
reactivity :
Human
sequence length :
260
specificity :
This HAGH antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 279-308 amino acids from the C-terminal region of human HAGH.
form :
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
storage stability :
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
WB~~1:100~1600
image1 heading :
Western Blot (WB)
other info1 :
Antigen Region: 279-308. Function: Thiolesterase that catalyzes the hydrolosis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid. Cellular Location: Isoform 1: Mitochondrion matrix. Tissue Location: Expressed in liver and kidney.
products categories :
Cell Biology; Metabolism; Neuroscience
products description :
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Two transcript variants encoding different isoforms have been found for this gene.
products references :
Davila, S., et al. Genes Immun. 11(3):232-238(2010). Limphong, P., et al. Biochemistry 48(23):5426-5434(2009). Antognelli, C., et al. Cancer Biol. Ther. 6(12):1880-1888(2007). Xu, Y., et al. J. Biol. Chem. 281(36):26702-26713(2006). Antognelli, C., et al. Cancer J 12(3):222-228(2006)
ncbi gi num :
94538320
ncbi acc num :
NP_001035517.1
ncbi gb acc num :
NM_001040427.1
uniprot acc num :
Q16775
ncbi mol weight :
33806
ncbi summary :
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
uniprot summary :
HAGH: Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Mitochondrial; EC 3.1.2.6; Hydrolase; Carbohydrate Metabolism - pyruvate. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: mitochondrial matrix; cytoplasm. Molecular Function: hydroxyacylglutathione hydrolase activity; zinc ion binding. Biological Process: glutathione biosynthetic process. Disease: Hydroxyacyl Glutathione Hydrolase Deficiency
size1 :
0.1 mL
price1 :
370 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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