catalog number :
MBS919642
products type :
ELISA Kit
products full name :
Human Interferon epsilon, IFNE ELISA Kit
products short name :
interferon, epsilon
products name syn :
Human Interferon epsilon (IFNE) ELISA kit; IFN-E; IFNE1; IFNT1; MGC119018; MGC119020; PRO655; IFN-epsilon; interferon epsilon 1; interferon tau-1; interferon-epsilon; interferon; epsilon
other names :
interferon epsilon; Interferon epsilon; interferon epsilon; IFN-epsilon; interferon tau-1; interferon-epsilon; interferon epsilon 1; interferon epsilon-1; interferon, epsilon; Interferon epsilon-1
products gene name :
IFNE
other gene names :
IFNE; IFNE; IFN-E; IFNE1; IFNT1; INFE1; PRO655; IFNE1; UNQ360/PRO655; IFN-epsilon
uniprot entry name :
IFNE_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human IFNE. No significant cross-reactivity or interference between human IFNE and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.6 pg/ml-1000 pg/ml. Sensitivity: Typically less than 3.9 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IFNE has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IFNE present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IFNE is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IFNE bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_795372.1
ncbi gb acc num :
NM_176891.4
ncbi mol weight :
24,414 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); RIG-I-like Receptor Signaling Pathway (117292); RIG-I-like Receptor Signaling Pathway (116128)
uniprot summary :
IFNE1: Belongs to the alpha/beta interferon family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 9p21.3. Cellular Component: extracellular space. Molecular Function: interferon-alpha/beta receptor binding; cytokine activity. Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; defense response to bacterium; natural killer cell activation during immune response; innate immune response; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein
size4 :
10x96-Strip-Wells