catalog number :
MBS916471
products type :
ELISA Kit
products full name :
Human chemokine (C-X-C motif) ligand 17, CXCL17 ELISA Kit
products short name :
chemokine (C-X-C motif) ligand 17 (CXCL17)
products name syn :
Human chemokine (C-X-C motif) ligand 17 (CXCL17) ELISA kit; CXCL17 DMC; Dcip1; MGC138300; UNQ473; VCC-1; VCC1; VEGF co-regulated chemokine 1; chemokine (C-X-C motif) ligand 17 (CXCL17)
other names :
Chemokine (C-X-C motif) ligand 17; VEGF coregulated chemokine 1; VEGF coregulated chemokine 1; C-X-C motif chemokine 17; VEGF co-regulated chemokine 1; dendritic cell and monocyte chemokine-like protein; chemokine (C-X-C motif) ligand 17; C-X-C motif chemokine 17; Dendritic cell and monocyte chemokine-like protein; DMC
products gene name :
CXCL17
other gene names :
CXCL17; CXCL17; DMC; VCC1; Dcip1; VCC-1; UNQ473; VCC1; UNQ473/PRO842; DMC
uniprot entry name :
VCC1_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human CXCL17. No significant cross-reactivity or interference between human CXCL17 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, cell culture supernates, urine and tissue homogenates. Assay Type: Sandwich. Detection Range: 125 pg/ml -8000 pg/ml. Sensitivity: The minimum detectable dose of human CXCL17 is typically less than 31.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CXCL17 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CXCL17 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CXCL17 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CXCL17 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
AAI12096.1
ncbi mol weight :
13,819 Da
uniprot summary :
CXCL17: Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: extracellular region. Biological Process: angiogenesis; chemotaxis; cell differentiation
size4 :
10x96-Strip-Wells