product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Programmed cell death 1 ligand 2, PDCD1LG2 ELISA Kit
catalog :
MBS916427
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS916427
products type :
ELISA Kit
products full name :
Human Programmed cell death 1 ligand 2, PDCD1LG2 ELISA Kit
products short name :
programmed cell death 1 ligand 2
products name syn :
Human Programmed cell death 1 ligand 2 (PDCD1LG2) ELISA kit; B7DC; Btdc; CD273; MGC142238; MGC142240; PD-L2; PDCD1L2; PDL2; bA574F11.2; PD-1-ligand 2; programmed death ligand 2; programmed cell death 1 ligand 2
other names :
programmed cell death 1 ligand 2; Programmed cell death 1 ligand 2; programmed cell death 1 ligand 2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7 dendritic cell molecule; programmed cell death 1 ligand 2; Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
products gene name :
PDCD1LG2
other gene names :
PDCD1LG2; PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC
uniprot entry name :
PD1L2_HUMAN
reactivity :
Human
sequence length :
273
specificity :
This assay has high sensitivity and excellent specificity for detection of Human PDCD1LG2. No significant cross-reactivity or interference between Human PDCD1LG2 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 46.88 pg/ml-3000 pg/ml. Sensitivity: 11.72 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PDCD1LG2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PDCD1LG2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PDCD1LG2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PDCD1LG2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
190014605
ncbi acc num :
NP_079515.2
ncbi gb acc num :
NM_025239.3
uniprot acc num :
Q9BQ51
ncbi mol weight :
30,957 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Costimulation By The CD28 Family Pathway (119552); Immune System Pathway (106386); PD-1 Signaling Pathway (119557)
uniprot summary :
PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 9p24.2. Cellular Component: integral to membrane; plasma membrane; endomembrane system. Biological Process: negative regulation of interleukin-10 production; negative regulation of interferon-gamma production; negative regulation of activated T cell proliferation; T cell costimulation; immune response; positive regulation of T cell proliferation
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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