catalog number :
MBS914849
products type :
ELISA Kit
products full name :
Human Putative humanin peptide, MT-RNR2 ELISA Kit
products short name :
[mitochondrially encoded 16S RNA]
products name syn :
[Human Putative humanin peptide (MT-RNR2) ELISA kit; MTRNR2; ; mitochondrially encoded 16S RNA]
other names :
[Putative humanin peptide; Putative humanin peptide]
products gene name :
[MT-RNR2]
other gene names :
[MT-RNR2]
uniprot entry name :
HUNIN_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human MT-ND6. No significant cross-reactivity or interference between human MT-ND6 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, Plasma, Tissue Homogenates, Cell Lysates. Assay Type: Quantitative Sandwich. Detection Range: 23.44 pg/ml-1500 pg/ml. Sensitivity: 5.86 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MT-ND6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any MT-ND6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MT-ND6 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MT-ND6 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi mol weight :
2,687 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
HUNIN: Plays a role as a neuroprotective factor. Protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Suppresses apoptosis by binding to BAX and preventing the translocation of BAX from the cytosol to mitochondria. Binds to IGFBP3 and specifically blocks IGFBP3-induced cell death Induces chemotaxis of mononuclear phagocytes via FPR2. Reduces the aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPRL1 to APP. Belongs to the humanin family.
size1 :
24-Strip-Wells (LIMIT 1)
size5 :
10x96-Strip-Wells