Human SNARE-associated protein Snapin, SNAPIN ELISA Kit | MyBioSource MBS914564 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human SNARE-associated protein Snapin, SNAPIN ELISA Kit

catalog :

MBS914564

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS914564

products type :

ELISA Kit

products full name :

Human SNARE-associated protein Snapin, SNAPIN ELISA Kit

products short name :

SNAP-associated protein

products name syn :

Human SNARE-associated protein Snapin (SNAPIN) ELISA kit; SNAPAP; SNAP-25-binding protein; SNARE associated protein snapin; SNAP-associated protein

other names :

SNARE-associated protein Snapin; SNARE-associated protein Snapin; SNARE-associated protein Snapin; BLOC-1 subunit 7; SNAP-25-binding protein; SNARE associated protein snapin; synaptosomal-associated protein 25-binding protein; biogenesis of lysosomal organelles complex-1, subunit 7; biogenesis of lysosome-related organelles complex 1 subunit 7; SNAP-associated protein; Biogenesis of lysosome-related organelles complex 1 subunit 7; BLOC-1 subunit 7; Synaptosomal-associated protein 25-binding protein; SNAP-associated protein

products gene name :

SNAPIN

other gene names :

SNAPIN; SNAPIN; BLOS7; SNAPAP; BLOC1S7; BLOC1S7; SNAP25BP; SNAPAP; BLOC-1 subunit 7; SNAP-associated protein

uniprot entry name :

SNAPN_HUMAN

reactivity :

Human

sequence length :

136

specificity :

This assay has high sensitivity and excellent specificity for detection of Human SNAPIN. No significant cross-reactivity or interference between Human SNAPIN and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, Cell lysates, tissue homogenates. Assay Type: Sandwich. Detection Range: 32 pg/ml-1200 pg/ml. Sensitivity: 8 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Cell Cycle. Protein Biological Process 3: Exocytosis

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SNAPIN has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for SNAPIN. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SNAPIN bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

6912674

ncbi acc num :

NP_036569.1

ncbi gb acc num :

NM_012437.5

uniprot acc num :

O95295

ncbi mol weight :

14,874 Da

ncbi pathways :

Clathrin Derived Vesicle Budding Pathway (119545); Golgi Associated Vesicle Biogenesis Pathway (119546); Membrane Trafficking Pathway (106160); Trans-Golgi Network Vesicle Budding Pathway (106165)

ncbi summary :

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

uniprot summary :

SNAPIN: a component of the SNARE complex of proteins that is required for synaptic vesicle docking and fusion. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells. Phosphorylation by PKA modulates its interaction with the SNARE complex. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 1q21.3. Cellular Component: Golgi membrane; Golgi apparatus; synaptic vesicle; transport vesicle; cytoplasmic vesicle membrane; synaptic vesicle membrane; perinuclear region of cytoplasm; nucleolus; synapse; cell junction; secretory granule. Molecular Function: SNARE binding; protein binding. Biological Process: viral reproduction; synaptic vesicle maturation; neurotransmitter secretion; synaptic vesicle transport; synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; synaptic vesicle exocytosis; melanosome organization and biogenesis; regulation of protein binding; anterograde synaptic vesicle transport; endosome to lysosome transport; anterograde axon cargo transport; neurite development

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage