Human High affinity immunoglobulin gamma Fc receptor I, FCGR1A ELISA Kit | MyBioSource MBS914465 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human High affinity immunoglobulin gamma Fc receptor I, FCGR1A ELISA Kit

catalog :

MBS914465

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS914465

products type :

ELISA Kit

products full name :

Human High affinity immunoglobulin gamma Fc receptor I, FCGR1A ELISA Kit

products short name :

Fc fragment of IgG, high affinity Ia, receptor (CD64)

products name syn :

Human High affinity immunoglobulin gamma Fc receptor I (FCGR1A) ELISA kit; CD64; CD64A; FCRI; FLJ18345; IGFR1; Fc fragment of IgG; high affinity Ia; receptor for (CD64) ; Fc gamma receptor; Fc-gamma RI; Fc-gamma receptor I A1; IgG Fc receptor I; Fc fragment of IgG; high affinity Ia; receptor (CD64)

other names :

high affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor I; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64

products gene name :

FCGR1A

other gene names :

FCGR1A; FCGR1A; CD64; FCRI; CD64A; IGFR1; FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa

uniprot entry name :

FCGR1_HUMAN

reactivity :

Human

sequence length :

374

specificity :

This assay has high sensitivity and excellent specificity for detection of human FCGR1A. No significant cross-reactivity or interference between human FCGR1A and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Detection Range: 0.78 ng/ml -50 ng/ml. Sensitivity: The minimum detectable dose of human FCGR1A is typically less than 0.2 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FCGR1A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FCGR1A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FCGR1A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FCGR1A bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

10835133

ncbi acc num :

NP_000557.1

ncbi gb acc num :

NM_000566.3

uniprot acc num :

P12314

ncbi mol weight :

42,632 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway (477126); Cytokine Signaling In Immune System Pathway (366171); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Immune System Pathway (106386)

ncbi summary :

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

uniprot summary :

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q21.2-q21.3. Cellular Component: early endosome membrane; plasma membrane; integral to membrane. Molecular Function: protein binding; IgG binding; receptor signaling protein activity. Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; phagocytosis, engulfment; signal transduction

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage