Human Interleukin-36 receptor antagonist protein, IL1F5 ELISA Kit | MyBioSource MBS914111 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Interleukin-36 receptor antagonist protein, IL1F5 ELISA Kit

catalog :

MBS914111

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS914111

products type :

ELISA Kit

products full name :

Human Interleukin-36 receptor antagonist protein, IL1F5 ELISA Kit

products short name :

interleukin 1 family, member 5 (delta)

products name syn :

Human Interleukin-36 receptor antagonist protein (IL1F5) ELISA kit; FIL1; FIL1 (DELTA); FIL1D; IL1HY1; IL1L1; IL1RP3; MGC29840; IL-1 related protein 3; IL-1F5 (IL-1HY1; FIL1-delta; IL-1RP3; IL-1L1; IL-1-delta) ; IL-1ra homolog; IL1F5 (Canonical product IL-1F5a) ; family of; interleukin 1 family; member 5 (delta)

other names :

interleukin-36 receptor antagonist protein; Interleukin-36 receptor antagonist protein; interleukin-36 receptor antagonist protein; IL-1ra homolog 1; interleukin-1 HY1; IL-1 related protein 3; interleukin-1-like protein 1; IL1F5 (Canonical product IL-1F5a); interleukin 1 family, member 5 (delta); interleukin-1 receptor antagonist homolog 1; IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta); interleukin 36 receptor antagonist; FIL1 delta; IL-1-related protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 receptor antagonist homolog 1; IL-1ra homolog 1; Interleukin-1-like protein 1; IL-1L1

products gene name :

IL1F5

other gene names :

IL36RN; IL36RN; FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; FIL1(DELTA); FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3; UNQ1896/PRO4342; IL-1RP3; IL-1HY1; IL-1 delta; IL-1F5; IL-1ra homolog 1; IL-1L1

uniprot entry name :

I36RA_HUMAN

reactivity :

Human

sequence length :

155

specificity :

This assay has high sensitivity and excellent specificity for detection of human IL1F5. No significant cross-reactivity or interference between human IL1F5 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, cell culture supernates, tissue homogenates. Assay Type: Sandwich. Detection Range: 7.8 pg/ml -500 pg/ml. Sensitivity: The minimum detectable dose of human IL1F5 is typically less than 1.95 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%.Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL1F5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL1F5 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL1F5 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL1F5 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

6912432

ncbi acc num :

NP_036407.1

ncbi gb acc num :

NM_012275.2

uniprot acc num :

Q9UBH0

ncbi mol weight :

16,962 Da

ncbi summary :

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

uniprot summary :

IL1F5: Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL- 1R1), that is present in epithelial barriers and takes part in local inflammatory response. Defects in IL36RN are the cause of psoriasis generalized pustular (PSORP). PSORP is a life-threatening disease defined by repeated flares of sudden onset consisting of diffuse erythematous skin eruption characterized by rapid coverage with pustules, high-grade fever, asthenia, marked leukocytosis, and elevated serum levels of C-reactive protein. Belongs to the IL-1 family. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 2q14. Cellular Component: extracellular space. Molecular Function: interleukin-1 receptor binding; cytokine activity; interleukin-1 receptor antagonist activity. Biological Process: negative regulation of interleukin-17 production; cytokine and chemokine mediated signaling pathway; negative regulation of interleukin-6 production; antifungal humoral response; innate immune response; negative regulation of cytokine and chemokine mediated signaling pathway. Disease: Psoriasis 14, Pustular

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage