product summary
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company name :
MyBioSource
product type :
antibody
product name :
CRACR2A Polyclonal Antibody
catalog :
MBS9133856
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using CRACR2A antibody at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
image 2 :
Immunohistochemistry of paraffinembedded mouse spleen using CRACR2A antibody (MBS128200) at dilution of 1:150 (40x lens).
product information
catalog number :
MBS9133856
products type :
Antibody
products full name :
CRACR2A Polyclonal Antibody
products short name :
[CRACR2A]
products name syn :
[EFCAB4B]
other names :
[EF-hand calcium-binding domain-containing protein 4B isoform a; EF-hand calcium-binding domain-containing protein 4B; EF-hand calcium-binding domain-containing protein 4B; calcium release activated channel regulator 2A; Calcium release-activated calcium channel regulator 2A; CRAC channel regulator 2A; Calcium release-activated channel regulator 2A]
products gene name :
[CRACR2A]
other gene names :
[CRACR2A; CRACR2A; EFCAB4B; EFCAB4B; CRAC channel regulator 2A]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
731
sequence :
MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQK
ETQEQTSGQLVMLRKAQEFFQTCDAEGKGFIARKDMQRL
HKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFF
FSQNNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDE
EAQFRMLMDRLGAQKVLEDESDVKQLWLQLKKEEPHLLS
NFEDF
ETQEQTSGQLVMLRKAQEFFQTCDAEGKGFIARKDMQRL
HKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFF
FSQNNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDE
EAQFRMLMDRLGAQKVLEDESDVKQLWLQLKKEEPHLLS
NFEDF
purity :
Affinity Purification
storage stability :
Store at -20 degree C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CRACR2A (NP_001138430.1).
other info2 :
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Cellular Location: Cytoplasm. Positive Samples: HeLa, Mouse liver, Rat liver
products categories :
Polyclonal Antibodies
ncbi gi num :
222418791
ncbi acc num :
NP_001138430.1
ncbi gb acc num :
NM_001144958.1
uniprot acc num :
Q9BSW2
ncbi mol weight :
Calculated: 45kDa; 83kDa. Observed: 45kDa
uniprot summary :
Ca2+-binding protein that plays a key role in store-operated Ca2+ entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+ resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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