product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLC19A1 Polyclonal Antibody
catalog :
MBS9132632
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9132632 image 1
Western blot analysis of extracts of various cell lines, using SLC19A1 antibody (MBS9132632) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
product information
catalog number :
MBS9132632
products type :
Antibody
products full name :
SLC19A1 Polyclonal Antibody
products short name :
[SLC19A1]
products name syn :
[SLC19A1; CHMD; FOLT; IFC1; REFC; RFC1; folate transporter 1]
other names :
[Folate transporter 1; Folate transporter 1; folate transporter 1; solute carrier family 19 member 1; Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; Solute carrier family 19 member 1]
products gene name :
[SLC19A1]
other gene names :
[SLC19A1; SLC19A1; CHMD; FOLT; IFC1; REFC; RFC1; FLOT1; RFC1; FOLT; IFC-1; RFC]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
591
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
Recommended dilution: WB: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_919231.1).
products categories :
Primary antibody
products description :
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.
ncbi gi num :
12643280
ncbi acc num :
P41440.3
uniprot acc num :
P41440
ncbi mol weight :
Calculated MW: 54kDa/60kDa/64kDa. Observed MW: 65kDa
ncbi pathways :
Antifolate Resistance Pathway (1440526); Antifolate Resistance Pathway (1440443); Folate Metabolism Pathway (198833); Metabolism Pathway (1269956); Metabolism Of Folate And Pterines Pathway (1270156); Metabolism Of Vitamins And Cofactors Pathway (1270144); Metabolism Of Water-soluble Vitamins And Cofactors Pathway (1270145); Vitamin Digestion And Absorption Pathway (199556); Vitamin Digestion And Absorption Pathway (199538)
ncbi summary :
The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
uniprot summary :
SLC19A1: a transporter protein. Transports reduced folate, antitumor agents and folate antagonists such as methotrexate. Apparently involved in methotrexate resistance in various cancers and neural tube defects. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: apical plasma membrane; basolateral plasma membrane; plasma membrane. Molecular Function: folic acid binding; folic acid transporter activity; methotrexate transporter activity; reduced folate carrier activity. Biological Process: folic acid metabolic process; folic acid transport; methotrexate transport
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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