product summary
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company name :
MyBioSource
product type :
antibody
product name :
PIP4K2B Polyclonal Antibody
catalog :
MBS9132428
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
image
image 1 :
Western blot analysis of extracts of various cell lines, using PIP4K2B antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
image 2 :
Immunofluorescence analysis of A549 cells using PIP4K2B antibody. Blue: DAPI for nuclear staining.
product information
catalog number :
MBS9132428
products type :
Antibody
products full name :
PIP4K2B Polyclonal Antibody
products short name :
[PIP4K2B]
products name syn :
[PIP4K2B; PI5P4KB; PIP5K2B; PIP5KIIB; PIP5KIIbeta; PIP5P4KB; phosphatidylinositol 5-phosphate 4-kinase type-2 beta]
other names :
[Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; phosphatidylinositol 5-phosphate 4-kinase type-2 beta; phosphatidylinositol-5-phosphate 4-kinase type 2 beta; 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2-beta; Phosphatidylinositol 5-phosphate 4-kinase type II beta; PI(5)P 4-kinase type II beta; PIP4KII-beta; PtdIns(5)P-4-kinase isoform 2-beta]
products gene name :
[PIP4K2B]
other gene names :
[PIP4K2B; PIP4K2B; PI5P4KB; PIP5K2B; PIP5KIIB; PIP5P4KB; PIP5KIIbeta; PIP5K2B; PI(5)P 4-kinase type II beta; PIP4KII-beta]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
416
purity :
Affinity Purification
form :
PBS with 50% Glycerol, pH 7.3
storage stability :
Store at -20 degree C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IF: 1:50 - 1:100
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PIP4K2B (NP_003550.1).
products categories :
Primary antibody
products description :
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.
ncbi gi num :
47605991
ncbi acc num :
P78356.1
uniprot acc num :
P78356
ncbi mol weight :
Calculated MW: 32kDa/47kDa. Observed MW: 47kDa
ncbi pathways :
3-phosphoinositide Biosynthesis Pathway (545314); B Cell Receptor Signaling Pathway (198909); D-myo-inositol (1,4,5)-trisphosphate Biosynthesis Pathway (545326); Inositol Phosphate Metabolism Pathway (82987); Inositol Phosphate Metabolism Pathway (362); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PI Metabolism Pathway (645332); Phosphatidylinositol Signaling System Pathway (83052); Phosphatidylinositol Signaling System Pathway (461)
ncbi summary :
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
PIP4K2B: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Homodimer. Binds TNFRSF1A. Interacts with PIP4K2A. Interaction with PIP4K2A suppresses ubiquitination by the SPOP/ CUL3 complex. Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.149; Kinase, lipid; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17q12. Cellular Component: autophagic vacuole; cytosol; nucleoplasm. Molecular Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; protein binding; protein homodimerization activity; receptor signaling protein activity. Biological Process: cell surface receptor linked signal transduction; phosphatidylinositol biosynthetic process; phospholipid metabolic process; regulation of autophagy; regulation of phosphoinositide 3-kinase cascade
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
275
size3 :
0.2 mL
price3 :
430
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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