product summary
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company name :
MyBioSource
product type :
antibody
product name :
KMT5B Polyclonal Antibody
catalog :
MBS9131880
quantity :
0.1 mL
price :
275 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9131880 image 1
Western blot analysis of extracts of HT-29 cells, using KMT5B antibody. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
product information
catalog number :
MBS9131880
products type :
Antibody
products full name :
KMT5B Polyclonal Antibody
products short name :
[KMT5B]
products name syn :
[KMT5B; CGI-85; CG185; SUV420H1; lysine methyltransferase 5B]
other names :
[Histone-lysine N-methyltransferase KMT5B; Histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase KMT5B; lysine methyltransferase 5B; Lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B]
products gene name :
[KMT5B]
other gene names :
[KMT5B; KMT5B; CGI85; CGI-85; SUV420H1; Su(var)4-20 homolog 1; Suv4-20h1]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
885
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at 4°C. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthetic peptide of human SUV420H1
products categories :
Primary antibody
products description :
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ncbi gi num :
332278247
ncbi acc num :
Q4FZB7.4
uniprot acc num :
Q4FZB7
ncbi mol weight :
Calculated: 31kDa/44kDa/99kDa. Observed: 92kDa
ncbi pathways :
Glucocorticoid Receptor Regulatory Network Pathway (138014); Lysine Degradation Pathway (82956); Lysine Degradation Pathway (320)
ncbi summary :
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
uniprot summary :
SUV420H1: a protein methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Strongly down-regulated in breast cancer cells. Belongs to the histone-lysine methyltransferase family. Suvar4-20 subfamily. Three alternatively-spliced isoforms have been described. Protein type: Amino Acid Metabolism - lysine degradation; EC 2.1.1.43; Methyltransferase; Methyltransferase, protein lysine. Chromosomal Location of Human Ortholog: 11q13.2. Cellular Component: nucleoplasm; nucleus. Molecular Function: histone-lysine N-methyltransferase activity
size1 :
0.1 mL
price1 :
275 USD
size2 :
0.2 mL
price2 :
430
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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