antibody

SLC39A8 Polyclonal Antibody

MBS9130903

0.05 mL

200 USD

polyclonal

rabbit

nonconjugated

human, mouse

Antibody

SLC39A8 Polyclonal Antibody

[SLC39A8]

[BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8]

[Zinc transporter ZIP8; Zinc transporter ZIP8; zinc transporter ZIP8; solute carrier family 39 member 8; BCG-induced integral membrane protein in monocyte clone 103 protein; LIV-1 subfamily of ZIP zinc transporter 6; LZT-Hs6; Solute carrier family 39 member 8; Zrt- and Irt-like protein 8; ZIP-8]

[SLC39A8]

[SLC39A8; SLC39A8; ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6; BIGM103; ZIP8; LZT-Hs6; ZIP-8]

Polyclonal

IgG

Rabbit

Human, Mouse

460

Affinity Purification

Store at -20°C. Avoid freeze/thaw cycles.

Western Blot (WB)

WB: 1:500 - 1:2000

Western Blot (WB)

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC39A8 (NP_071437.3)

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Calculated MW: 43kDa/48kDa/49kDa. Observed MW: 50kDa

Primary antibody

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

74733496

Q9C0K1.1

Q9C0K1

Metal Ion SLC Transporters Pathway (1269930); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1269923); Zinc Influx Into Cells By The SLC39 Gene Family Pathway (1269933); Zinc Transporters Pathway (1269931)

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]

SLC39A8: Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family. Chromosomal Location of Human Ortholog: 4q24. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: zinc ion transmembrane transporter activity. Biological Process: cellular zinc ion homeostasis; zinc ion transport. Disease: Congenital Disorder Of Glycosylation, Type Iin

0.05 mL

200 USD

0.1 mL

275

0.2 mL

430