catalog number :
MBS9129795
products full name :
PAPD7 Polyclonal Antibody
products short name :
[PAPD7]
other names :
[non-canonical poly(A) RNA polymerase PAPD7 isoform 2; Non-canonical poly(A) RNA polymerase PAPD7; non-canonical poly(A) RNA polymerase PAPD7; PAP associated domain containing 7; DNA polymerase sigma; LAK-1; PAP-associated domain-containing protein 7; TRAMP-like complex polyadenylate polymerase; Terminal uridylyltransferase 5; TUTase 5; Topoisomerase-related function protein 4-1; TRF4-1]
products gene name :
[PAPD7]
other gene names :
[PAPD7; PAPD7; LAK1; POLK; POLS; TRF4; LAK-1; TRF41; TRF4-1; TUTASE5; POLS; TRF4; TUTase 5; TRF4-1]
uniprot entry name :
PAPD7_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:1000
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Immunogen: Recombinant funsion protein containing a sequence corresponding to amino acids 303-542 of Human (PAPD7) (NP_008930.1). Calculated MW: 59kDa/82kDa. Observed MW: 82kDa
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
ncbi acc num :
NP_001165276.1
ncbi gb acc num :
NM_001171805.1
ncbi pathways :
RNA Degradation Pathway (117291); RNA Degradation Pathway (116127); TRAMP Complex Pathway (413459); TRAMP Complex Pathway (468399)
ncbi summary :
The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jan 2010]
uniprot summary :
POLS: DNA polymerase, probably involved in DNA repair. May play a role in sister chromatid cohesion. Does not play a role in replication-dependent histone mRNA degradation. Belongs to the DNA polymerase type-B-like family. Protein type: DNA repair, damage; EC 2.7.7.19; DNA replication; Transferase. Chromosomal Location of Human Ortholog: 5p15. Cellular Component: cytoplasm; nucleoplasm; nucleus. Molecular Function: DNA binding; DNA-directed DNA polymerase activity; metal ion binding; polynucleotide adenylyltransferase activity; SMC protein binding. Biological Process: cell division; double-strand break repair; mitotic chromosome condensation; response to drug; sister chromatid cohesion