catalog number :
MBS9129731
products full name :
TAS1R3 Polyclonal Antibody
products short name :
[TAS1R3]
other names :
[taste receptor type 1 member 3; Taste receptor type 1 member 3; taste receptor type 1 member 3; taste 1 receptor member 3; Sweet taste receptor T1R3]
products gene name :
[TAS1R3]
other gene names :
[TAS1R3; TAS1R3; T1R3; T1R3; TR3]
uniprot entry name :
TS1R3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity purification
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB)
app notes :
WB: 1:1000 - 1:4000
image1 heading :
Western Blot (WB)
other info1 :
Source: Rabbit. Immunogen: Recombinant protein of human TAS1R3
other info2 :
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
products categories :
Polyclonal
products description :
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response.
ncbi acc num :
NP_689414.1
ncbi gb acc num :
NM_152228.2
ncbi mol weight :
Calculated: 93kDa. Observed: 95-105kDa
ncbi pathways :
Carbohydrate Digestion And Absorption Pathway (170720); Carbohydrate Digestion And Absorption Pathway (170654); Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway (1269573); GPCR Ligand Binding Pathway (1269544); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543); Taste Transduction Pathway (83088); Taste Transduction Pathway (499)
ncbi summary :
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
uniprot summary :
TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. Protein type: GPCR, family 3; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 1p36.33. Cellular Component: integral to membrane; plasma membrane. Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity. Biological Process: detection of chemical stimulus involved in sensory perception of sweet taste; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; sensory perception of umami taste